The steroidal glycoalkaloids solamargine and solasonine in Solanum plants

S. S.S. Al Sinani, E. A. Eltayeb

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Glycoalkaloids are a class of nitrogen-containing steroidal glycosides, they are biologically active secondary metabolites and are commonly found in plants of the genus Solanum. These compounds have been the subject of many literature papers, they occur widely in the human diet including potato (Solanum tuberosum), tomato (Solanum lycopersicum) and aubergine (Solanum melongena) and are known to induce toxicity. Therefore, from the food safety and biological activity perspectives further information is required regarding their analysis, toxicity and bioavailability. A comprehensive review of different analytical methods of quantification of two glycoalkaloids solamargine and solasonine and their bioactivity particularly focused on toxicity, anticancer activity and mechanisms of action is presented in this paper.

Original languageEnglish
Pages (from-to)253-269
Number of pages17
JournalSouth African Journal of Botany
Volume112
DOIs
Publication statusPublished - Sep 1 2017

Fingerprint

glycoalkaloids
Solanum
toxicity
Solanum melongena
Solanum lycopersicum
Solanum tuberosum
secondary metabolites
analytical methods
food safety
glycosides
bioavailability
bioactive properties
mechanism of action
tomatoes
potatoes
nitrogen
diet

Keywords

  • Anticancer
  • Secondary metabolites
  • Solamargine
  • Solanaceae
  • Solasonine
  • Steroidal glycoalkaloids

ASJC Scopus subject areas

  • Plant Science

Cite this

The steroidal glycoalkaloids solamargine and solasonine in Solanum plants. / Al Sinani, S. S.S.; Eltayeb, E. A.

In: South African Journal of Botany, Vol. 112, 01.09.2017, p. 253-269.

Research output: Contribution to journalReview article

@article{bb1000dd31294532aedb4d7903dbef11,
title = "The steroidal glycoalkaloids solamargine and solasonine in Solanum plants",
abstract = "Glycoalkaloids are a class of nitrogen-containing steroidal glycosides, they are biologically active secondary metabolites and are commonly found in plants of the genus Solanum. These compounds have been the subject of many literature papers, they occur widely in the human diet including potato (Solanum tuberosum), tomato (Solanum lycopersicum) and aubergine (Solanum melongena) and are known to induce toxicity. Therefore, from the food safety and biological activity perspectives further information is required regarding their analysis, toxicity and bioavailability. A comprehensive review of different analytical methods of quantification of two glycoalkaloids solamargine and solasonine and their bioactivity particularly focused on toxicity, anticancer activity and mechanisms of action is presented in this paper.",
keywords = "Anticancer, Secondary metabolites, Solamargine, Solanaceae, Solasonine, Steroidal glycoalkaloids",
author = "{Al Sinani}, {S. S.S.} and Eltayeb, {E. A.}",
year = "2017",
month = "9",
day = "1",
doi = "10.1016/j.sajb.2017.06.002",
language = "English",
volume = "112",
pages = "253--269",
journal = "South African Journal of Botany",
issn = "0254-6299",
publisher = "Elsevier",

}

TY - JOUR

T1 - The steroidal glycoalkaloids solamargine and solasonine in Solanum plants

AU - Al Sinani, S. S.S.

AU - Eltayeb, E. A.

PY - 2017/9/1

Y1 - 2017/9/1

N2 - Glycoalkaloids are a class of nitrogen-containing steroidal glycosides, they are biologically active secondary metabolites and are commonly found in plants of the genus Solanum. These compounds have been the subject of many literature papers, they occur widely in the human diet including potato (Solanum tuberosum), tomato (Solanum lycopersicum) and aubergine (Solanum melongena) and are known to induce toxicity. Therefore, from the food safety and biological activity perspectives further information is required regarding their analysis, toxicity and bioavailability. A comprehensive review of different analytical methods of quantification of two glycoalkaloids solamargine and solasonine and their bioactivity particularly focused on toxicity, anticancer activity and mechanisms of action is presented in this paper.

AB - Glycoalkaloids are a class of nitrogen-containing steroidal glycosides, they are biologically active secondary metabolites and are commonly found in plants of the genus Solanum. These compounds have been the subject of many literature papers, they occur widely in the human diet including potato (Solanum tuberosum), tomato (Solanum lycopersicum) and aubergine (Solanum melongena) and are known to induce toxicity. Therefore, from the food safety and biological activity perspectives further information is required regarding their analysis, toxicity and bioavailability. A comprehensive review of different analytical methods of quantification of two glycoalkaloids solamargine and solasonine and their bioactivity particularly focused on toxicity, anticancer activity and mechanisms of action is presented in this paper.

KW - Anticancer

KW - Secondary metabolites

KW - Solamargine

KW - Solanaceae

KW - Solasonine

KW - Steroidal glycoalkaloids

UR - http://www.scopus.com/inward/record.url?scp=85034107017&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85034107017&partnerID=8YFLogxK

U2 - 10.1016/j.sajb.2017.06.002

DO - 10.1016/j.sajb.2017.06.002

M3 - Review article

VL - 112

SP - 253

EP - 269

JO - South African Journal of Botany

JF - South African Journal of Botany

SN - 0254-6299

ER -