Syntheses of Galbulimima alkaloids

Uwe Rinner, Christoph Lentsch, Christian Aichinger

Research output: Contribution to journalReview article

25 Citations (Scopus)

Abstract

The bark of the rain forest tree Galbulimima belgraveana has been identified as a rich source of fascinating natural products and so far 28 unique alkaloids have been isolated. The chemical interest in Galbulimima alkaloids started with the discovery of the promising biological activities of himbacine. Fifteen years after the first total synthesis of himbacine, this class of natural product still inspires, with the structurally more complex congeners himandrine, himgaline, and G.B. 13 as highly challenging synthetic targets. This review article summarizes and discusses all syntheses of Galbulimima alkaloids published to date. 1 Introduction 2 Syntheses of Galbulimima Alkaloids 2.1 Class I Alkaloids 2.2 Class II Alkaloids 2.3 Class III Alkaloids 3 Conclusion.

Original languageEnglish
Article numberE27410SS
Pages (from-to)3763-3784
Number of pages22
JournalSynthesis
Issue number22
DOIs
Publication statusPublished - 2010

Keywords

  • Diels-Alder reaction
  • fused-ring systems
  • Galbulimima alkaloids
  • heterocycles
  • natural products
  • total synthesis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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  • Cite this

    Rinner, U., Lentsch, C., & Aichinger, C. (2010). Syntheses of Galbulimima alkaloids. Synthesis, (22), 3763-3784. [E27410SS]. https://doi.org/10.1055/s-0030-1258251