TY - JOUR
T1 - Syntheses of Galbulimima alkaloids
AU - Rinner, Uwe
AU - Lentsch, Christoph
AU - Aichinger, Christian
PY - 2010
Y1 - 2010
N2 - The bark of the rain forest tree Galbulimima belgraveana has been identified as a rich source of fascinating natural products and so far 28 unique alkaloids have been isolated. The chemical interest in Galbulimima alkaloids started with the discovery of the promising biological activities of himbacine. Fifteen years after the first total synthesis of himbacine, this class of natural product still inspires, with the structurally more complex congeners himandrine, himgaline, and G.B. 13 as highly challenging synthetic targets. This review article summarizes and discusses all syntheses of Galbulimima alkaloids published to date. 1 Introduction 2 Syntheses of Galbulimima Alkaloids 2.1 Class I Alkaloids 2.2 Class II Alkaloids 2.3 Class III Alkaloids 3 Conclusion.
AB - The bark of the rain forest tree Galbulimima belgraveana has been identified as a rich source of fascinating natural products and so far 28 unique alkaloids have been isolated. The chemical interest in Galbulimima alkaloids started with the discovery of the promising biological activities of himbacine. Fifteen years after the first total synthesis of himbacine, this class of natural product still inspires, with the structurally more complex congeners himandrine, himgaline, and G.B. 13 as highly challenging synthetic targets. This review article summarizes and discusses all syntheses of Galbulimima alkaloids published to date. 1 Introduction 2 Syntheses of Galbulimima Alkaloids 2.1 Class I Alkaloids 2.2 Class II Alkaloids 2.3 Class III Alkaloids 3 Conclusion.
KW - Diels-Alder reaction
KW - Galbulimima alkaloids
KW - fused-ring systems
KW - heterocycles
KW - natural products
KW - total synthesis
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U2 - 10.1055/s-0030-1258251
DO - 10.1055/s-0030-1258251
M3 - Review article
AN - SCOPUS:78149464050
SN - 0039-7881
SP - 3763
EP - 3784
JO - Synthesis
JF - Synthesis
IS - 22
M1 - E27410SS
ER -