Psychiatric manifestations in Wilson's disease: A cross-sectional analysis

A. Shanmugiah, S. Sinha, A. B. Taly*, L. K. Prashanth, M. Tomar, G. R. Arunodaya, Janardhana Y.C. Reddy, S. Khanna

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

53 Citations (Scopus)


Behavioral and psychiatric abnormalities in Wilson's disease (WD) have a variable frequency and spectrum. This study involved evaluation of the psychiatric comorbidities in patients of Wilson's disease, using structured clinical interview for DSM-IV Axis-I disorders (SCID). Among the 50 confirmed patients with Wilson's disease recruited for this study, 12 patients (24%) fulfilled the diagnostic criteria for syndromic psychiatric diagnosis: bipolar affective disorder (18%), major depression (4%), and dysthymia (2%). Formal assessment of psychopathology in all patients with Wilson's disease may have therapeutic significance.

Original languageEnglish
Pages (from-to)81-85
Number of pages5
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Issue number1
Publication statusPublished - 2008
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health


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