Abstract
The concentrations of gamma-amino butyric acid (GABA) and glutamate were measured in the brains of chickens which were treated with furazolidone (FZ) or nitrofurazone (NF) at oral doses of 12.5, or 50 mg/kg for 5 days. At the end of the treatment, the birds lost about 9% of their bodyweight when on the small dose of FZ or NF and about 18% when on the high doses. Both drugs produced dose-dependent increases in the concentrations of GABA and glutamate which were statistically significant at doses of 25 and 50 mg/kg of NF, and 50 mg/kg of FZ.
| Original language | English |
|---|---|
| Pages (from-to) | 363-366 |
| Number of pages | 4 |
| Journal | Clinical and Experimental Pharmacology and Physiology |
| Volume | 16 |
| Issue number | 5 |
| Publication status | Published - 1989 |
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ASJC Scopus subject areas
- Physiology
- Pharmacology (medical)
- Pharmacology, Toxicology and Pharmaceutics(all)
Cite this
Effect of furazolidone and nitrofurazone on brain gamma-amino butyric acid and glutamate concentrations in chickens. / Ali, B. H.
In: Clinical and Experimental Pharmacology and Physiology, Vol. 16, No. 5, 1989, p. 363-366.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of furazolidone and nitrofurazone on brain gamma-amino butyric acid and glutamate concentrations in chickens
AU - Ali, B. H.
PY - 1989
Y1 - 1989
N2 - The concentrations of gamma-amino butyric acid (GABA) and glutamate were measured in the brains of chickens which were treated with furazolidone (FZ) or nitrofurazone (NF) at oral doses of 12.5, or 50 mg/kg for 5 days. At the end of the treatment, the birds lost about 9% of their bodyweight when on the small dose of FZ or NF and about 18% when on the high doses. Both drugs produced dose-dependent increases in the concentrations of GABA and glutamate which were statistically significant at doses of 25 and 50 mg/kg of NF, and 50 mg/kg of FZ.
AB - The concentrations of gamma-amino butyric acid (GABA) and glutamate were measured in the brains of chickens which were treated with furazolidone (FZ) or nitrofurazone (NF) at oral doses of 12.5, or 50 mg/kg for 5 days. At the end of the treatment, the birds lost about 9% of their bodyweight when on the small dose of FZ or NF and about 18% when on the high doses. Both drugs produced dose-dependent increases in the concentrations of GABA and glutamate which were statistically significant at doses of 25 and 50 mg/kg of NF, and 50 mg/kg of FZ.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024348813&partnerID=8YFLogxK
M3 - Article
VL - 16
SP - 363
EP - 366
JO - Clinical and Experimental Pharmacology and Physiology
JF - Clinical and Experimental Pharmacology and Physiology
SN - 0305-1870
IS - 5
ER -