Abstract
The concentrations of gamma-amino butyric acid (GABA) and glutamate were measured in the brains of chickens which were treated with furazolidone (FZ) or nitrofurazone (NF) at oral doses of 12.5, or 50 mg/kg for 5 days. At the end of the treatment, the birds lost about 9% of their bodyweight when on the small dose of FZ or NF and about 18% when on the high doses. Both drugs produced dose-dependent increases in the concentrations of GABA and glutamate which were statistically significant at doses of 25 and 50 mg/kg of NF, and 50 mg/kg of FZ.
Original language | English |
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Pages (from-to) | 363-366 |
Number of pages | 4 |
Journal | Clinical and Experimental Pharmacology and Physiology |
Volume | 16 |
Issue number | 5 |
Publication status | Published - 1989 |
ASJC Scopus subject areas
- Physiology
- Pharmacology (medical)
- Pharmacology, Toxicology and Pharmaceutics(all)