Acardia syndrome coexisting with gastroschisis in the co-twin

O. A. Habbal, R. K. Kenue*, P. Venugopalan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


Acardia syndrome is a rare complication affecting monozygotic twins, wherein one twin fails to develop brain and thoracic structures, while the co-twin most often develops normally. In this report we present an acardiac anencephalic monozygotic twin with an omphalocoele and a co-twin with severe intrauterine growth retardation and gastroschisis. The presence of gastroschisis in the co-twin of an acardiac foetus is rare. The embryologic basis of the twin reversed arterial perfusion (TRAP) sequence is outlined and the observed anomalies in the co-twin traced to a similar pathophysiology.

Original languageEnglish
Pages (from-to)45-47
Number of pages3
JournalClinical Dysmorphology
Issue number1
Publication statusPublished - Jan 2005


  • Acardia
  • Gastroschisis
  • Intrauterine growth retardation
  • Monozygotic twins

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Anatomy
  • Pathology and Forensic Medicine
  • Genetics(clinical)


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