For the first time a sequential injection technique has been employed in a full kinetic investigation as well as for a kinetic procedure utilizing the fixed-time method. The complexation reaction of bromazepam with iron(II) in hydrochloric acid was studied using spectrophotometric detection at λ(max) 585 nm for the product formed. A rate law was offered, which was found to be consistent with the postulated reaction mechanism. From the observed kinetics it was found that the fixed-time method utilized at 100 s using 0.0100 mol dm-3 iron(II) and 0.0115 mol dm-3 HCl had optimal conditions for the determination of bromazepam in the range 5.0 x 10-4-1.5 x 10-3 mol dm-3. The method was found to be suitable for the determination of bromazepam in drug formulations.
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