Relationship between white blood cell count and in-hospital outcomes in acute coronary syndrome patients from the Middle East

Kadhim Sulaiman*, Ibrahim Al-Zakwani, Prashanth Panduranga, Jassim Al-Suwaidi, Alawi A. Alsheikh-Ali, Wael Al Mahmeed, Haitham Amin, Ahmed Al-Mutarreb, Khalid Alhabib, Jawad Al-Lawati, Mohammed Zubaid

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةمراجعة النظراء

3 اقتباسات (Scopus)

ملخص

We evaluated the relationship between admission white blood cell (WBC) count and in-hospital outcomes in acute coronary syndrome (ACS) patients from the Middle East. Data were analyzed from 7806 consecutive patients with ACS who were divided into 4 groups (G) according to their WBC count (×109/L; G1: <6.00; G2: 6.00-9.99; G3: 10.00-11.99; G4: ≥12.00). After significant covariate adjustment, those in G4 were 68% more likely to have cardiogenic shock than those in G1 (95% confidence interval [CI]: 1.05-2.68; P =.030) and G2 (odds ratio [OR], 2.02; 95% CI: 1.51-2.71; P <.001). Those in G4 were 2.02 times (95% CI: 1.11-3.67; P =.021) and 65% (95% CI: 1.17-2.32; P =.004) more likely to die in hospital than those in G1 and G2, respectively. Admission WBC count is an independent risk factor for in-hospital cardiogenic shock and mortality, in Middle Eastern patients with ACS. Novel therapeutic agents targeting WBCs in patients with ACS may improve outcomes.

اللغة الأصليةEnglish
الصفحات (من إلى)24-29
عدد الصفحات6
دوريةAngiology
مستوى الصوت63
رقم الإصدار1
المعرِّفات الرقمية للأشياء
حالة النشرPublished - يناير 2012

ASJC Scopus subject areas

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