TY - JOUR
T1 - Pharmacological, therapeutic and toxicological properties of furazolidone
T2 - Some recent research
AU - Ali, B. H.
PY - 1999
Y1 - 1999
N2 - Some of the recent publications on the pharmacological, therapeutic and toxicological properties of the antimicrobial agent furazolidone (FZ) are briefly reviewed. In animals, most of the recently published papers focus on (1) the methodology of measuring the residues of the drug and its metabolites in edible tissues: (2) the carcinogenicity and genotoxicity of FZ; (3) the cellular and molecular basis of FZ-induced cardiomyopathy, and the action of different cardioprotectant drugs thereon; and (4) hormonal effects. In humans, the use of FZ as an anti-ulcer drug and in controlling infectious diseases, especially opportunistic infections in AIDS patients, is described.
AB - Some of the recent publications on the pharmacological, therapeutic and toxicological properties of the antimicrobial agent furazolidone (FZ) are briefly reviewed. In animals, most of the recently published papers focus on (1) the methodology of measuring the residues of the drug and its metabolites in edible tissues: (2) the carcinogenicity and genotoxicity of FZ; (3) the cellular and molecular basis of FZ-induced cardiomyopathy, and the action of different cardioprotectant drugs thereon; and (4) hormonal effects. In humans, the use of FZ as an anti-ulcer drug and in controlling infectious diseases, especially opportunistic infections in AIDS patients, is described.
KW - Carcinogen
KW - Cardiomyopathy
KW - Furazolidone
KW - Pharmacology
KW - Therapeutics
KW - Toxicity
UR - http://www.scopus.com/inward/record.url?scp=0032886658&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032886658&partnerID=8YFLogxK
U2 - 10.1023/A:1006333608012
DO - 10.1023/A:1006333608012
M3 - Review article
C2 - 10543364
AN - SCOPUS:0032886658
SN - 0165-7380
VL - 23
SP - 343
EP - 360
JO - Veterinary Research Communications
JF - Veterinary Research Communications
IS - 6
ER -