Pharmacological, therapeutic and toxicological properties of furazolidone: Some recent research

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Abstract

Some of the recent publications on the pharmacological, therapeutic and toxicological properties of the antimicrobial agent furazolidone (FZ) are briefly reviewed. In animals, most of the recently published papers focus on (1) the methodology of measuring the residues of the drug and its metabolites in edible tissues: (2) the carcinogenicity and genotoxicity of FZ; (3) the cellular and molecular basis of FZ-induced cardiomyopathy, and the action of different cardioprotectant drugs thereon; and (4) hormonal effects. In humans, the use of FZ as an anti-ulcer drug and in controlling infectious diseases, especially opportunistic infections in AIDS patients, is described.

Original languageEnglish
Pages (from-to)343-360
Number of pages18
JournalVeterinary Research Communications
Volume23
Issue number6
DOIs
Publication statusPublished - 1999

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Keywords

  • Carcinogen
  • Cardiomyopathy
  • Furazolidone
  • Pharmacology
  • Therapeutics
  • Toxicity

ASJC Scopus subject areas

  • veterinary(all)

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