A coarse grained model for DNA and polymer packaging: Statics and dynamics

Issam Ali, Davide Marenduzzo*, C. Micheletti, J. M. Yeomans

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةمراجعة النظراء

3 اقتباسات (Scopus)

ملخص

We present a numerical characterization of the statics and dynamics of the packaging of a semi-flexible polymer inside a sphere. The study is motivated by recent experiments on the packaging of DNA inside viral capsids. It is found that the force required to confine the coarse-grained polymer is in fair agreement with that found in experiments for the packaging of the phi29 bacteriophage genome. Despite its schematic nature, the model is capable of reproducing the most salient dynamical features of packaging experiments such as the presence of pauses during individual packaging processes and the trend of the resisting force as a function of chain packed fraction.

اللغة الأصليةEnglish
الصفحات (من إلى)115-117
عدد الصفحات3
دوريةJournal of Theoretical Medicine
مستوى الصوت6
رقم الإصدار2
المعرِّفات الرقمية للأشياء
حالة النشرPublished - يونيو 2005

ASJC Scopus subject areas

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