Voltammetric quantitation of nitazoxanide by glassy carbon electrode

Rajeev Jain; Rajeev Kumar Yadav; Jahangir Ahmad Rather

doi:10.1016/j.jpha.2013.07.005

Voltammetric quantitation of nitazoxanide by glassy carbon electrode

Rajeev Jain^*, Rajeev Kumar Yadav, Jahangir Ahmad Rather

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

9 Citations (SciVal)

Abstract

The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson (B-R) buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 20-140 μg/mL. The limit of detection (LOD) and limit of quantification (LOQ) was calculated to be 5.23 μg/mL and 17.45 μg/mL, respectively.

Original language	English
Pages (from-to)	452-455
Number of pages	4
Journal	Journal of Pharmaceutical Analysis
Volume	3
Issue number	6
DOIs	https://doi.org/10.1016/j.jpha.2013.07.005
Publication status	Published - Dec 2013

Keywords

Glassy carbon electrode
Nitazoxanide
Pharmaceutical formulation
Squarewave voltammetry

ASJC Scopus subject areas

Analytical Chemistry
Pharmacy
Pharmaceutical Science
Drug Discovery
Spectroscopy
Electrochemistry

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10.1016/j.jpha.2013.07.005

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title = "Voltammetric quantitation of nitazoxanide by glassy carbon electrode",

abstract = "The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson (B-R) buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 20-140 μg/mL. The limit of detection (LOD) and limit of quantification (LOQ) was calculated to be 5.23 μg/mL and 17.45 μg/mL, respectively.",

keywords = "Glassy carbon electrode, Nitazoxanide, Pharmaceutical formulation, Squarewave voltammetry",

author = "Rajeev Jain and {Kumar Yadav}, Rajeev and {Ahmad Rather}, Jahangir",

year = "2013",

month = dec,

doi = "10.1016/j.jpha.2013.07.005",

language = "English",

volume = "3",

pages = "452--455",

journal = "Journal of Pharmaceutical Analysis",

issn = "2095-1779",

publisher = "Xi'an Jiaotong University",

number = "6",

}

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T1 - Voltammetric quantitation of nitazoxanide by glassy carbon electrode

AU - Jain, Rajeev

AU - Kumar Yadav, Rajeev

AU - Ahmad Rather, Jahangir

PY - 2013/12

Y1 - 2013/12

N2 - The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson (B-R) buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 20-140 μg/mL. The limit of detection (LOD) and limit of quantification (LOQ) was calculated to be 5.23 μg/mL and 17.45 μg/mL, respectively.

AB - The present study reports voltammetric reduction of nitazoxanide in Britton-Robinson (B-R) buffer by cyclic and square-wave voltammetry at glassy carbon electrode. A versatile fully validated voltammetric method for quantitative determination of nitazoxanide in pharmaceutical formulation has been proposed. A squrewave peak current was linear over the nitazoxanide concentration in the range of 20-140 μg/mL. The limit of detection (LOD) and limit of quantification (LOQ) was calculated to be 5.23 μg/mL and 17.45 μg/mL, respectively.

KW - Glassy carbon electrode

KW - Nitazoxanide

KW - Pharmaceutical formulation

KW - Squarewave voltammetry

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JO - Journal of Pharmaceutical Analysis

JF - Journal of Pharmaceutical Analysis

IS - 6

ER -

Voltammetric quantitation of nitazoxanide by glassy carbon electrode

Abstract

Keywords

ASJC Scopus subject areas

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