Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent sadult

Ramachandiran Nandhagopal, Nelly Khmeleva, B. Jayakrishnan, Teresa White, Faisal Al Azri, Jojy George, Anna Heintzman, Khalfan A. Al Zeedy, Lucy Rorke-Adams, Arunodaya R. Gujjar, D. Scott Schmid, Abdullah Al-Asmi, Maria A. Nagel, Poovathoor Chacko Jacob, Don Gilden

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Varicella zoster virus (VZV) pneumonitis and brainstem encephalitis developed in an immunocompetent adult without rash. Chest computed tomography exhibited nodularity; lung biopsy revealed multinucleated giant cells, Cowdry A inclusions, VZV antigen, and DNA. Varicella zoster virus central nervous system disease was verified by cerebrospinal fluid (CSF) anti-VZV IgG antibody with reduced serum/CSF ratios.

Original languageEnglish
JournalOpen Forum Infectious Diseases
Volume1
Issue number2
DOIs
Publication statusPublished - 2014

Fingerprint

Human Herpesvirus 3
Encephalitis
Exanthema
Brain Stem
Pneumonia
Cerebrospinal Fluid
Central Nervous System Diseases
Giant Cells
Thorax
Immunoglobulin G
Tomography
Biopsy
Antigens
Lung
Antibodies
DNA
Serum

Keywords

  • Absence of rash
  • Brainstem encephalitis
  • Pneumonitis
  • VZV

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology

Cite this

Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent sadult. / Nandhagopal, Ramachandiran; Khmeleva, Nelly; Jayakrishnan, B.; White, Teresa; Al Azri, Faisal; George, Jojy; Heintzman, Anna; Al Zeedy, Khalfan A.; Rorke-Adams, Lucy; Gujjar, Arunodaya R.; Schmid, D. Scott; Al-Asmi, Abdullah; Nagel, Maria A.; Jacob, Poovathoor Chacko; Gilden, Don.

In: Open Forum Infectious Diseases, Vol. 1, No. 2, 2014.

Research output: Contribution to journalArticle

Nandhagopal, Ramachandiran ; Khmeleva, Nelly ; Jayakrishnan, B. ; White, Teresa ; Al Azri, Faisal ; George, Jojy ; Heintzman, Anna ; Al Zeedy, Khalfan A. ; Rorke-Adams, Lucy ; Gujjar, Arunodaya R. ; Schmid, D. Scott ; Al-Asmi, Abdullah ; Nagel, Maria A. ; Jacob, Poovathoor Chacko ; Gilden, Don. / Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent sadult. In: Open Forum Infectious Diseases. 2014 ; Vol. 1, No. 2.
@article{78b9a81d961a4b56af61123e65cd3a6f,
title = "Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent sadult",
abstract = "Varicella zoster virus (VZV) pneumonitis and brainstem encephalitis developed in an immunocompetent adult without rash. Chest computed tomography exhibited nodularity; lung biopsy revealed multinucleated giant cells, Cowdry A inclusions, VZV antigen, and DNA. Varicella zoster virus central nervous system disease was verified by cerebrospinal fluid (CSF) anti-VZV IgG antibody with reduced serum/CSF ratios.",
keywords = "Absence of rash, Brainstem encephalitis, Pneumonitis, VZV",
author = "Ramachandiran Nandhagopal and Nelly Khmeleva and B. Jayakrishnan and Teresa White and {Al Azri}, Faisal and Jojy George and Anna Heintzman and {Al Zeedy}, {Khalfan A.} and Lucy Rorke-Adams and Gujjar, {Arunodaya R.} and Schmid, {D. Scott} and Abdullah Al-Asmi and Nagel, {Maria A.} and Jacob, {Poovathoor Chacko} and Don Gilden",
year = "2014",
doi = "10.1093/ofid/ofu064",
language = "English",
volume = "1",
journal = "Open Forum Infectious Diseases",
issn = "2328-8957",
publisher = "Oxford University Press",
number = "2",

}

TY - JOUR

T1 - Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent sadult

AU - Nandhagopal, Ramachandiran

AU - Khmeleva, Nelly

AU - Jayakrishnan, B.

AU - White, Teresa

AU - Al Azri, Faisal

AU - George, Jojy

AU - Heintzman, Anna

AU - Al Zeedy, Khalfan A.

AU - Rorke-Adams, Lucy

AU - Gujjar, Arunodaya R.

AU - Schmid, D. Scott

AU - Al-Asmi, Abdullah

AU - Nagel, Maria A.

AU - Jacob, Poovathoor Chacko

AU - Gilden, Don

PY - 2014

Y1 - 2014

N2 - Varicella zoster virus (VZV) pneumonitis and brainstem encephalitis developed in an immunocompetent adult without rash. Chest computed tomography exhibited nodularity; lung biopsy revealed multinucleated giant cells, Cowdry A inclusions, VZV antigen, and DNA. Varicella zoster virus central nervous system disease was verified by cerebrospinal fluid (CSF) anti-VZV IgG antibody with reduced serum/CSF ratios.

AB - Varicella zoster virus (VZV) pneumonitis and brainstem encephalitis developed in an immunocompetent adult without rash. Chest computed tomography exhibited nodularity; lung biopsy revealed multinucleated giant cells, Cowdry A inclusions, VZV antigen, and DNA. Varicella zoster virus central nervous system disease was verified by cerebrospinal fluid (CSF) anti-VZV IgG antibody with reduced serum/CSF ratios.

KW - Absence of rash

KW - Brainstem encephalitis

KW - Pneumonitis

KW - VZV

UR - http://www.scopus.com/inward/record.url?scp=84974647923&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84974647923&partnerID=8YFLogxK

U2 - 10.1093/ofid/ofu064

DO - 10.1093/ofid/ofu064

M3 - Article

VL - 1

JO - Open Forum Infectious Diseases

JF - Open Forum Infectious Diseases

SN - 2328-8957

IS - 2

ER -