Varicella zoster virus pneumonitis and brainstem encephalitis without skin rash in an immunocompetent sadult

Ramachandiran Nandhagopal, Nelly Khmeleva, B. Jayakrishnan, Teresa White, Faisal Al Azri, Jojy George, Anna Heintzman, Khalfan A. Al Zeedy, Lucy Rorke-Adams, Arunodaya R. Gujjar, D. Scott Schmid, Abdullah Al-Asmi, Maria A. Nagel, Poovathoor Chacko Jacob, Don Gilden

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Varicella zoster virus (VZV) pneumonitis and brainstem encephalitis developed in an immunocompetent adult without rash. Chest computed tomography exhibited nodularity; lung biopsy revealed multinucleated giant cells, Cowdry A inclusions, VZV antigen, and DNA. Varicella zoster virus central nervous system disease was verified by cerebrospinal fluid (CSF) anti-VZV IgG antibody with reduced serum/CSF ratios.

Original languageEnglish
JournalOpen Forum Infectious Diseases
Volume1
Issue number2
DOIs
Publication statusPublished - 2014

Keywords

  • Absence of rash
  • Brainstem encephalitis
  • Pneumonitis
  • VZV

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology

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