TY - JOUR
T1 - Validation of R-hf risk score for risk stratification in ischemic heart failure patients
T2 - A prospective cohort study
AU - Rajan, Rajesh
AU - Soman, Suman Omana
AU - Al Jarallah, Mohammed
AU - Kobalava, Zhanna
AU - Dashti, Raja
AU - Al Zakwani, Ibrahim
AU - Al Balool, Joud
AU - Tse, Gary
AU - Setiya, Parul
AU - Brady, Peter A.
AU - Al-Saber, Ahmad
AU - Vijayaraghavan, Govindan
N1 - © 2022 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.
PY - 2022/8/1
Y1 - 2022/8/1
N2 - BACKGROUND: The aim of this study was to validate R-heart failure (R-hf) risk score in ischemic heart failure patients.METHODS: We prospectively recruited a cohort of 179 ischemic and 107 non-ischemic heart failure patients. This study mainly focused on ischemic heart failure patients. Non-ischemic heart failure patients were included for the purpose of validation of the risk score in various heart failure groups. Patients were stratified in high risk, moderate risk and low risk groups according to R-hf risk score.RESULTS: A total of 179 participants with ischemic heart failure were included. Based on R-hf risk score, 82 had high risk, 50 had moderate risk and 47 had low risk heart failure scores. More than half of the patients having R-hf score of <5 had renal failure (n = 91, 50.8%) and anemia (n = 99, 55.3%). Notably, HFrEF was more prevalent in patients with high risk score (74, 90.2%). Patients with high risk score had significantly higher creatinine (2.63 ± 1.96, p < 0.001), Troponin-T HS (59.9 ± 38.0, p < 0.001) and PRO BNP (17842 ± 6684, p < 0.001) when compared to patients with low and moderate risk score. Patients with low risk score had significantly higher Hb (13.2 ± 1.85, p < 0.001), Albumin (3.69 ± 0.42, p < 0.001) and GFR (90.0 ± 8.04, p < 0.001). A R-hf score of <5 was a significant predictor of mortality in ischemic (OR = 50.34; 95% CI [16.94-194.00, p < 0.001) and non-ischemic (OR = 46.34; 95% CI [12.97-225.39], p < 0.001) heart failure patients.CONCLUSIONS: Lower R-hf risk score is a significant predictor of mortality in ischemic and non-ischemic heart failure patients. Risk score can be accessed at https://www.hfriskcalc.in.
AB - BACKGROUND: The aim of this study was to validate R-heart failure (R-hf) risk score in ischemic heart failure patients.METHODS: We prospectively recruited a cohort of 179 ischemic and 107 non-ischemic heart failure patients. This study mainly focused on ischemic heart failure patients. Non-ischemic heart failure patients were included for the purpose of validation of the risk score in various heart failure groups. Patients were stratified in high risk, moderate risk and low risk groups according to R-hf risk score.RESULTS: A total of 179 participants with ischemic heart failure were included. Based on R-hf risk score, 82 had high risk, 50 had moderate risk and 47 had low risk heart failure scores. More than half of the patients having R-hf score of <5 had renal failure (n = 91, 50.8%) and anemia (n = 99, 55.3%). Notably, HFrEF was more prevalent in patients with high risk score (74, 90.2%). Patients with high risk score had significantly higher creatinine (2.63 ± 1.96, p < 0.001), Troponin-T HS (59.9 ± 38.0, p < 0.001) and PRO BNP (17842 ± 6684, p < 0.001) when compared to patients with low and moderate risk score. Patients with low risk score had significantly higher Hb (13.2 ± 1.85, p < 0.001), Albumin (3.69 ± 0.42, p < 0.001) and GFR (90.0 ± 8.04, p < 0.001). A R-hf score of <5 was a significant predictor of mortality in ischemic (OR = 50.34; 95% CI [16.94-194.00, p < 0.001) and non-ischemic (OR = 46.34; 95% CI [12.97-225.39], p < 0.001) heart failure patients.CONCLUSIONS: Lower R-hf risk score is a significant predictor of mortality in ischemic and non-ischemic heart failure patients. Risk score can be accessed at https://www.hfriskcalc.in.
KW - Chronic kidney disease
KW - Ischemic heart failure
KW - Left ventricular dysfunction
KW - Mortality
KW - R-Hf risk score
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UR - http://www.scopus.com/inward/citedby.url?scp=85135720176&partnerID=8YFLogxK
U2 - 10.1016/j.amsu.2022.104333
DO - 10.1016/j.amsu.2022.104333
M3 - Article
C2 - 35992211
AN - SCOPUS:85135720176
SN - 2049-0801
VL - 80
JO - Annals of Medicine and Surgery
JF - Annals of Medicine and Surgery
M1 - 104333
ER -