Tumor-induced hypercalcemia

predictors of early mortality.

I. Siddiqui, H. S. Bhally, Q. Niaz, I. A. Burney

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

OBJECTIVE: To delineate the demographics and predictors of early mortality associated with tumor-induced hypercalcemia (TIH) amongst cancer patients in Pakistan. SETTING: A tertiary care hospital in Pakistan. PATIENTS AND METHODS: Retrospective analysis of patients with cancers, presenting with TIH and admitted to the hospital between January 1988 and December 1997, was carried out. RESULTS: Eighty-four patients (56 males and 28 females) were diagnosed to have TIH. The mean age at the time of presentation was 55 +/- 14 years. Twenty-five percent of the patients each had multiple myeloma and hepatocellular carcinoma whereas 20% of the patients had underlying breast cancer. Other malignancies included lung cancer, gall bladder cancer and colorectal carcinomas. Univariate analysis revealed male sex (p < 0.04), underlying diagnosis other than multiple myeloma (p < 0.025) and a high TLC (p < 0.05) at presentation, as predictors of an early mortality. CONCLUSION: Multiple myeloma, hepatoma and breast carcinoma were common cancers causing TIH. One-third patients died within first few days. Male sex, a high white cell count and an underlying diagnosis other than multiple myeloma predicted early mortality.

Original languageEnglish
Pages (from-to)361-364
Number of pages4
JournalJournal of the Pakistan Medical Association
Volume52
Issue number8
Publication statusPublished - Aug 2002

Fingerprint

Hypercalcemia
Mortality
Multiple Myeloma
Neoplasms
Pakistan
Hepatocellular Carcinoma
Breast Neoplasms
Gallbladder Neoplasms
Tertiary Healthcare
Urinary Bladder Neoplasms
Tertiary Care Centers
Colorectal Neoplasms
Lung Neoplasms
Cell Count
Demography

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Tumor-induced hypercalcemia : predictors of early mortality. / Siddiqui, I.; Bhally, H. S.; Niaz, Q.; Burney, I. A.

In: Journal of the Pakistan Medical Association, Vol. 52, No. 8, 08.2002, p. 361-364.

Research output: Contribution to journalArticle

Siddiqui, I. ; Bhally, H. S. ; Niaz, Q. ; Burney, I. A. / Tumor-induced hypercalcemia : predictors of early mortality. In: Journal of the Pakistan Medical Association. 2002 ; Vol. 52, No. 8. pp. 361-364.
@article{f0e3ddca40764e2ea42f014dbf20512b,
title = "Tumor-induced hypercalcemia: predictors of early mortality.",
abstract = "OBJECTIVE: To delineate the demographics and predictors of early mortality associated with tumor-induced hypercalcemia (TIH) amongst cancer patients in Pakistan. SETTING: A tertiary care hospital in Pakistan. PATIENTS AND METHODS: Retrospective analysis of patients with cancers, presenting with TIH and admitted to the hospital between January 1988 and December 1997, was carried out. RESULTS: Eighty-four patients (56 males and 28 females) were diagnosed to have TIH. The mean age at the time of presentation was 55 +/- 14 years. Twenty-five percent of the patients each had multiple myeloma and hepatocellular carcinoma whereas 20{\%} of the patients had underlying breast cancer. Other malignancies included lung cancer, gall bladder cancer and colorectal carcinomas. Univariate analysis revealed male sex (p < 0.04), underlying diagnosis other than multiple myeloma (p < 0.025) and a high TLC (p < 0.05) at presentation, as predictors of an early mortality. CONCLUSION: Multiple myeloma, hepatoma and breast carcinoma were common cancers causing TIH. One-third patients died within first few days. Male sex, a high white cell count and an underlying diagnosis other than multiple myeloma predicted early mortality.",
author = "I. Siddiqui and Bhally, {H. S.} and Q. Niaz and Burney, {I. A.}",
year = "2002",
month = "8",
language = "English",
volume = "52",
pages = "361--364",
journal = "JPMA. The Journal of the Pakistan Medical Association",
issn = "0030-9982",
publisher = "Pakistan Medical Association",
number = "8",

}

TY - JOUR

T1 - Tumor-induced hypercalcemia

T2 - predictors of early mortality.

AU - Siddiqui, I.

AU - Bhally, H. S.

AU - Niaz, Q.

AU - Burney, I. A.

PY - 2002/8

Y1 - 2002/8

N2 - OBJECTIVE: To delineate the demographics and predictors of early mortality associated with tumor-induced hypercalcemia (TIH) amongst cancer patients in Pakistan. SETTING: A tertiary care hospital in Pakistan. PATIENTS AND METHODS: Retrospective analysis of patients with cancers, presenting with TIH and admitted to the hospital between January 1988 and December 1997, was carried out. RESULTS: Eighty-four patients (56 males and 28 females) were diagnosed to have TIH. The mean age at the time of presentation was 55 +/- 14 years. Twenty-five percent of the patients each had multiple myeloma and hepatocellular carcinoma whereas 20% of the patients had underlying breast cancer. Other malignancies included lung cancer, gall bladder cancer and colorectal carcinomas. Univariate analysis revealed male sex (p < 0.04), underlying diagnosis other than multiple myeloma (p < 0.025) and a high TLC (p < 0.05) at presentation, as predictors of an early mortality. CONCLUSION: Multiple myeloma, hepatoma and breast carcinoma were common cancers causing TIH. One-third patients died within first few days. Male sex, a high white cell count and an underlying diagnosis other than multiple myeloma predicted early mortality.

AB - OBJECTIVE: To delineate the demographics and predictors of early mortality associated with tumor-induced hypercalcemia (TIH) amongst cancer patients in Pakistan. SETTING: A tertiary care hospital in Pakistan. PATIENTS AND METHODS: Retrospective analysis of patients with cancers, presenting with TIH and admitted to the hospital between January 1988 and December 1997, was carried out. RESULTS: Eighty-four patients (56 males and 28 females) were diagnosed to have TIH. The mean age at the time of presentation was 55 +/- 14 years. Twenty-five percent of the patients each had multiple myeloma and hepatocellular carcinoma whereas 20% of the patients had underlying breast cancer. Other malignancies included lung cancer, gall bladder cancer and colorectal carcinomas. Univariate analysis revealed male sex (p < 0.04), underlying diagnosis other than multiple myeloma (p < 0.025) and a high TLC (p < 0.05) at presentation, as predictors of an early mortality. CONCLUSION: Multiple myeloma, hepatoma and breast carcinoma were common cancers causing TIH. One-third patients died within first few days. Male sex, a high white cell count and an underlying diagnosis other than multiple myeloma predicted early mortality.

UR - http://www.scopus.com/inward/record.url?scp=0036673301&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036673301&partnerID=8YFLogxK

M3 - Article

VL - 52

SP - 361

EP - 364

JO - JPMA. The Journal of the Pakistan Medical Association

JF - JPMA. The Journal of the Pakistan Medical Association

SN - 0030-9982

IS - 8

ER -