Toxicities, kinetics and degradation pathways investigation of ciprofloxacin degradation using iron-mediated H2O2 based advanced oxidation processes

Noor S. Shah, Allah Ditta Rizwan, Javed Ali Khan, Murtaza Sayed, Zia Ul Haq Khan, Behzad Murtaza, Jibran Iqbal, Salah Ud Din, Muhammad Imran, Muhammad Nadeem, Ala Al-Muhtaseb, Nawshad Muhammad, Hasan M. Khan, Moinuddin Ghauri, Gohar Zaman

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Ciprofloxacin (CIP) is a widespread emerging water pollutant and thus its removal from aquatic environment is vital. The use of Fe3+/H2O2 and Fe2+/H2O2 resulted in 38 and 64% removal of CIP (8.0 ppm), respectively, within 80 min reaction time (pH 5.8, [H2O2]0 = 80 ppm, and [iron]0 = 20 ppm). Low pH, high temperature, high dose of H2O2 and Fe2+, and low CIP concentration facilitated removal of CIP. The radical scavenger studies proved in situ generated [rad]OH to be involved primarily in the removal of CIP. The effect of temperature was used to estimate enthalpy and activation energies of the removal of CIP. At 800 min reaction time, the Fe2+/H2O2 resulted in 54% mineralization of CIP using 16.0 ppm [CIP]0, 320.0 ppm [H2O2]0, and 40.0 ppm [Fe2+]0. The potential degradation pathways of CIP established from the degradation of CIP by [rad]OH and products evolved was found to be initiated at C6 through the loss of fluoride ion. The acute and chronic toxicities of CIP and its degradation products were estimated with the final product found to be non-toxic. The results suggest that Fe2+/H2O2-mediated AOPs have high potential for degradation as well as toxicity elimination of CIP and its degradation products.

Original languageEnglish
Pages (from-to)473-482
Number of pages10
JournalProcess Safety and Environmental Protection
Volume117
DOIs
Publication statusPublished - Jul 1 2018

Fingerprint

Ciprofloxacin
Toxicity
Iron
toxicity
oxidation
iron
Degradation
kinetics
Oxidation
degradation
Kinetics
scavenger
enthalpy
fluoride
activation energy
aquatic environment
Enthalpy
Activation energy
removal
mineralization

Keywords

  • AOPs
  • Ciprofloxacin
  • Degradation pathways
  • Toxicity assessment
  • Water treatment

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Chemistry
  • Chemical Engineering(all)
  • Safety, Risk, Reliability and Quality

Cite this

Toxicities, kinetics and degradation pathways investigation of ciprofloxacin degradation using iron-mediated H2O2 based advanced oxidation processes. / Shah, Noor S.; Rizwan, Allah Ditta; Khan, Javed Ali; Sayed, Murtaza; Khan, Zia Ul Haq; Murtaza, Behzad; Iqbal, Jibran; Din, Salah Ud; Imran, Muhammad; Nadeem, Muhammad; Al-Muhtaseb, Ala; Muhammad, Nawshad; Khan, Hasan M.; Ghauri, Moinuddin; Zaman, Gohar.

In: Process Safety and Environmental Protection, Vol. 117, 01.07.2018, p. 473-482.

Research output: Contribution to journalArticle

Shah, NS, Rizwan, AD, Khan, JA, Sayed, M, Khan, ZUH, Murtaza, B, Iqbal, J, Din, SU, Imran, M, Nadeem, M, Al-Muhtaseb, A, Muhammad, N, Khan, HM, Ghauri, M & Zaman, G 2018, 'Toxicities, kinetics and degradation pathways investigation of ciprofloxacin degradation using iron-mediated H2O2 based advanced oxidation processes', Process Safety and Environmental Protection, vol. 117, pp. 473-482. https://doi.org/10.1016/j.psep.2018.05.020
Shah, Noor S. ; Rizwan, Allah Ditta ; Khan, Javed Ali ; Sayed, Murtaza ; Khan, Zia Ul Haq ; Murtaza, Behzad ; Iqbal, Jibran ; Din, Salah Ud ; Imran, Muhammad ; Nadeem, Muhammad ; Al-Muhtaseb, Ala ; Muhammad, Nawshad ; Khan, Hasan M. ; Ghauri, Moinuddin ; Zaman, Gohar. / Toxicities, kinetics and degradation pathways investigation of ciprofloxacin degradation using iron-mediated H2O2 based advanced oxidation processes. In: Process Safety and Environmental Protection. 2018 ; Vol. 117. pp. 473-482.
@article{2c48b076e88e4b0c9b4d6d59e827c029,
title = "Toxicities, kinetics and degradation pathways investigation of ciprofloxacin degradation using iron-mediated H2O2 based advanced oxidation processes",
abstract = "Ciprofloxacin (CIP) is a widespread emerging water pollutant and thus its removal from aquatic environment is vital. The use of Fe3+/H2O2 and Fe2+/H2O2 resulted in 38 and 64{\%} removal of CIP (8.0 ppm), respectively, within 80 min reaction time (pH 5.8, [H2O2]0 = 80 ppm, and [iron]0 = 20 ppm). Low pH, high temperature, high dose of H2O2 and Fe2+, and low CIP concentration facilitated removal of CIP. The radical scavenger studies proved in situ generated [rad]OH to be involved primarily in the removal of CIP. The effect of temperature was used to estimate enthalpy and activation energies of the removal of CIP. At 800 min reaction time, the Fe2+/H2O2 resulted in 54{\%} mineralization of CIP using 16.0 ppm [CIP]0, 320.0 ppm [H2O2]0, and 40.0 ppm [Fe2+]0. The potential degradation pathways of CIP established from the degradation of CIP by [rad]OH and products evolved was found to be initiated at C6 through the loss of fluoride ion. The acute and chronic toxicities of CIP and its degradation products were estimated with the final product found to be non-toxic. The results suggest that Fe2+/H2O2-mediated AOPs have high potential for degradation as well as toxicity elimination of CIP and its degradation products.",
keywords = "AOPs, Ciprofloxacin, Degradation pathways, Toxicity assessment, Water treatment",
author = "Shah, {Noor S.} and Rizwan, {Allah Ditta} and Khan, {Javed Ali} and Murtaza Sayed and Khan, {Zia Ul Haq} and Behzad Murtaza and Jibran Iqbal and Din, {Salah Ud} and Muhammad Imran and Muhammad Nadeem and Ala Al-Muhtaseb and Nawshad Muhammad and Khan, {Hasan M.} and Moinuddin Ghauri and Gohar Zaman",
year = "2018",
month = "7",
day = "1",
doi = "10.1016/j.psep.2018.05.020",
language = "English",
volume = "117",
pages = "473--482",
journal = "Process Safety and Environmental Protection",
issn = "0957-5820",
publisher = "Institution of Chemical Engineers",

}

TY - JOUR

T1 - Toxicities, kinetics and degradation pathways investigation of ciprofloxacin degradation using iron-mediated H2O2 based advanced oxidation processes

AU - Shah, Noor S.

AU - Rizwan, Allah Ditta

AU - Khan, Javed Ali

AU - Sayed, Murtaza

AU - Khan, Zia Ul Haq

AU - Murtaza, Behzad

AU - Iqbal, Jibran

AU - Din, Salah Ud

AU - Imran, Muhammad

AU - Nadeem, Muhammad

AU - Al-Muhtaseb, Ala

AU - Muhammad, Nawshad

AU - Khan, Hasan M.

AU - Ghauri, Moinuddin

AU - Zaman, Gohar

PY - 2018/7/1

Y1 - 2018/7/1

N2 - Ciprofloxacin (CIP) is a widespread emerging water pollutant and thus its removal from aquatic environment is vital. The use of Fe3+/H2O2 and Fe2+/H2O2 resulted in 38 and 64% removal of CIP (8.0 ppm), respectively, within 80 min reaction time (pH 5.8, [H2O2]0 = 80 ppm, and [iron]0 = 20 ppm). Low pH, high temperature, high dose of H2O2 and Fe2+, and low CIP concentration facilitated removal of CIP. The radical scavenger studies proved in situ generated [rad]OH to be involved primarily in the removal of CIP. The effect of temperature was used to estimate enthalpy and activation energies of the removal of CIP. At 800 min reaction time, the Fe2+/H2O2 resulted in 54% mineralization of CIP using 16.0 ppm [CIP]0, 320.0 ppm [H2O2]0, and 40.0 ppm [Fe2+]0. The potential degradation pathways of CIP established from the degradation of CIP by [rad]OH and products evolved was found to be initiated at C6 through the loss of fluoride ion. The acute and chronic toxicities of CIP and its degradation products were estimated with the final product found to be non-toxic. The results suggest that Fe2+/H2O2-mediated AOPs have high potential for degradation as well as toxicity elimination of CIP and its degradation products.

AB - Ciprofloxacin (CIP) is a widespread emerging water pollutant and thus its removal from aquatic environment is vital. The use of Fe3+/H2O2 and Fe2+/H2O2 resulted in 38 and 64% removal of CIP (8.0 ppm), respectively, within 80 min reaction time (pH 5.8, [H2O2]0 = 80 ppm, and [iron]0 = 20 ppm). Low pH, high temperature, high dose of H2O2 and Fe2+, and low CIP concentration facilitated removal of CIP. The radical scavenger studies proved in situ generated [rad]OH to be involved primarily in the removal of CIP. The effect of temperature was used to estimate enthalpy and activation energies of the removal of CIP. At 800 min reaction time, the Fe2+/H2O2 resulted in 54% mineralization of CIP using 16.0 ppm [CIP]0, 320.0 ppm [H2O2]0, and 40.0 ppm [Fe2+]0. The potential degradation pathways of CIP established from the degradation of CIP by [rad]OH and products evolved was found to be initiated at C6 through the loss of fluoride ion. The acute and chronic toxicities of CIP and its degradation products were estimated with the final product found to be non-toxic. The results suggest that Fe2+/H2O2-mediated AOPs have high potential for degradation as well as toxicity elimination of CIP and its degradation products.

KW - AOPs

KW - Ciprofloxacin

KW - Degradation pathways

KW - Toxicity assessment

KW - Water treatment

UR - http://www.scopus.com/inward/record.url?scp=85047823281&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85047823281&partnerID=8YFLogxK

U2 - 10.1016/j.psep.2018.05.020

DO - 10.1016/j.psep.2018.05.020

M3 - Article

VL - 117

SP - 473

EP - 482

JO - Process Safety and Environmental Protection

JF - Process Safety and Environmental Protection

SN - 0957-5820

ER -