Special issues related to hematopoietic SCT in the Eastern Mediterranean region and the first regional activity report

M. D. Aljurf, S. Z. Zaidi, H. El Solh, F. Hussain, A. Ghavamzadeh, H. K. Mahmoud, T. Shamsi, T. Ben Othman, M. M. Sarhan, D. Dennison, A. Ibrahim, S. Benchekroun, N. Chaudhri, B. Labar, M. Horowitz, D. Niederwieser, A. Gratwohl

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Although several centers are now performing allogeneic hematopoietic SCT (HSCT) in the Eastern Mediterranean (EM) region, the availability is still limited. Special issues including compatible donor availability and potential for alternative donor programs are discussed. In comparison to Europe and North America, differences in patterns of diseases and pre-HSCT general status, particularly for patients with BM failure, are described. Other differences including high sero-positivity for CMV, hepatitis B and C infection, and specific observations about GVHD and its relation to genetically homogeneous communities are also discussed. We report that a total of 17 HSCT programs (performing five or more HSCTs annually) exist in 9 countries of the EM region. Only six programs are currently reporting to European Group for Blood and Marrow Transplantation or Center for International Blood and Marrow Transplantation Research. A total of 7617 HSCTs have been performed by these programs including 5701 allogeneic HSCTs. The area has low-HSCT team density (1.56 teams per 10 million inhabitants vs 14.43 in Europe) and very low-HSCT team distribution (0.27 teams per 10000 sq km area vs <1-6 teams in Europe). Gross national income per capita had no clear association with low-HSCT activity. Much improvement in infrastructure and formation of an EM regional HSCT registry are needed.

Original languageEnglish
Pages (from-to)1-12
Number of pages12
JournalBone Marrow Transplantation
Volume43
Issue number1
DOIs
Publication statusPublished - 2009

Fingerprint

Mediterranean Region
Tissue Donors
Hepatitis C
North America
Hepatitis B
Registries
Transplantation
Bone Marrow
Infection
Research

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Aljurf, M. D., Zaidi, S. Z., El Solh, H., Hussain, F., Ghavamzadeh, A., Mahmoud, H. K., ... Gratwohl, A. (2009). Special issues related to hematopoietic SCT in the Eastern Mediterranean region and the first regional activity report. Bone Marrow Transplantation, 43(1), 1-12. https://doi.org/10.1038/bmt.2008.389

Special issues related to hematopoietic SCT in the Eastern Mediterranean region and the first regional activity report. / Aljurf, M. D.; Zaidi, S. Z.; El Solh, H.; Hussain, F.; Ghavamzadeh, A.; Mahmoud, H. K.; Shamsi, T.; Othman, T. Ben; Sarhan, M. M.; Dennison, D.; Ibrahim, A.; Benchekroun, S.; Chaudhri, N.; Labar, B.; Horowitz, M.; Niederwieser, D.; Gratwohl, A.

In: Bone Marrow Transplantation, Vol. 43, No. 1, 2009, p. 1-12.

Research output: Contribution to journalArticle

Aljurf, MD, Zaidi, SZ, El Solh, H, Hussain, F, Ghavamzadeh, A, Mahmoud, HK, Shamsi, T, Othman, TB, Sarhan, MM, Dennison, D, Ibrahim, A, Benchekroun, S, Chaudhri, N, Labar, B, Horowitz, M, Niederwieser, D & Gratwohl, A 2009, 'Special issues related to hematopoietic SCT in the Eastern Mediterranean region and the first regional activity report', Bone Marrow Transplantation, vol. 43, no. 1, pp. 1-12. https://doi.org/10.1038/bmt.2008.389
Aljurf, M. D. ; Zaidi, S. Z. ; El Solh, H. ; Hussain, F. ; Ghavamzadeh, A. ; Mahmoud, H. K. ; Shamsi, T. ; Othman, T. Ben ; Sarhan, M. M. ; Dennison, D. ; Ibrahim, A. ; Benchekroun, S. ; Chaudhri, N. ; Labar, B. ; Horowitz, M. ; Niederwieser, D. ; Gratwohl, A. / Special issues related to hematopoietic SCT in the Eastern Mediterranean region and the first regional activity report. In: Bone Marrow Transplantation. 2009 ; Vol. 43, No. 1. pp. 1-12.
@article{9bd9dbd71bbc487e8c3718437968a1b8,
title = "Special issues related to hematopoietic SCT in the Eastern Mediterranean region and the first regional activity report",
abstract = "Although several centers are now performing allogeneic hematopoietic SCT (HSCT) in the Eastern Mediterranean (EM) region, the availability is still limited. Special issues including compatible donor availability and potential for alternative donor programs are discussed. In comparison to Europe and North America, differences in patterns of diseases and pre-HSCT general status, particularly for patients with BM failure, are described. Other differences including high sero-positivity for CMV, hepatitis B and C infection, and specific observations about GVHD and its relation to genetically homogeneous communities are also discussed. We report that a total of 17 HSCT programs (performing five or more HSCTs annually) exist in 9 countries of the EM region. Only six programs are currently reporting to European Group for Blood and Marrow Transplantation or Center for International Blood and Marrow Transplantation Research. A total of 7617 HSCTs have been performed by these programs including 5701 allogeneic HSCTs. The area has low-HSCT team density (1.56 teams per 10 million inhabitants vs 14.43 in Europe) and very low-HSCT team distribution (0.27 teams per 10000 sq km area vs <1-6 teams in Europe). Gross national income per capita had no clear association with low-HSCT activity. Much improvement in infrastructure and formation of an EM regional HSCT registry are needed.",
author = "Aljurf, {M. D.} and Zaidi, {S. Z.} and {El Solh}, H. and F. Hussain and A. Ghavamzadeh and Mahmoud, {H. K.} and T. Shamsi and Othman, {T. Ben} and Sarhan, {M. M.} and D. Dennison and A. Ibrahim and S. Benchekroun and N. Chaudhri and B. Labar and M. Horowitz and D. Niederwieser and A. Gratwohl",
year = "2009",
doi = "10.1038/bmt.2008.389",
language = "English",
volume = "43",
pages = "1--12",
journal = "Bone Marrow Transplantation",
issn = "0268-3369",
publisher = "Nature Publishing Group",
number = "1",

}

TY - JOUR

T1 - Special issues related to hematopoietic SCT in the Eastern Mediterranean region and the first regional activity report

AU - Aljurf, M. D.

AU - Zaidi, S. Z.

AU - El Solh, H.

AU - Hussain, F.

AU - Ghavamzadeh, A.

AU - Mahmoud, H. K.

AU - Shamsi, T.

AU - Othman, T. Ben

AU - Sarhan, M. M.

AU - Dennison, D.

AU - Ibrahim, A.

AU - Benchekroun, S.

AU - Chaudhri, N.

AU - Labar, B.

AU - Horowitz, M.

AU - Niederwieser, D.

AU - Gratwohl, A.

PY - 2009

Y1 - 2009

N2 - Although several centers are now performing allogeneic hematopoietic SCT (HSCT) in the Eastern Mediterranean (EM) region, the availability is still limited. Special issues including compatible donor availability and potential for alternative donor programs are discussed. In comparison to Europe and North America, differences in patterns of diseases and pre-HSCT general status, particularly for patients with BM failure, are described. Other differences including high sero-positivity for CMV, hepatitis B and C infection, and specific observations about GVHD and its relation to genetically homogeneous communities are also discussed. We report that a total of 17 HSCT programs (performing five or more HSCTs annually) exist in 9 countries of the EM region. Only six programs are currently reporting to European Group for Blood and Marrow Transplantation or Center for International Blood and Marrow Transplantation Research. A total of 7617 HSCTs have been performed by these programs including 5701 allogeneic HSCTs. The area has low-HSCT team density (1.56 teams per 10 million inhabitants vs 14.43 in Europe) and very low-HSCT team distribution (0.27 teams per 10000 sq km area vs <1-6 teams in Europe). Gross national income per capita had no clear association with low-HSCT activity. Much improvement in infrastructure and formation of an EM regional HSCT registry are needed.

AB - Although several centers are now performing allogeneic hematopoietic SCT (HSCT) in the Eastern Mediterranean (EM) region, the availability is still limited. Special issues including compatible donor availability and potential for alternative donor programs are discussed. In comparison to Europe and North America, differences in patterns of diseases and pre-HSCT general status, particularly for patients with BM failure, are described. Other differences including high sero-positivity for CMV, hepatitis B and C infection, and specific observations about GVHD and its relation to genetically homogeneous communities are also discussed. We report that a total of 17 HSCT programs (performing five or more HSCTs annually) exist in 9 countries of the EM region. Only six programs are currently reporting to European Group for Blood and Marrow Transplantation or Center for International Blood and Marrow Transplantation Research. A total of 7617 HSCTs have been performed by these programs including 5701 allogeneic HSCTs. The area has low-HSCT team density (1.56 teams per 10 million inhabitants vs 14.43 in Europe) and very low-HSCT team distribution (0.27 teams per 10000 sq km area vs <1-6 teams in Europe). Gross national income per capita had no clear association with low-HSCT activity. Much improvement in infrastructure and formation of an EM regional HSCT registry are needed.

UR - http://www.scopus.com/inward/record.url?scp=58549083544&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58549083544&partnerID=8YFLogxK

U2 - 10.1038/bmt.2008.389

DO - 10.1038/bmt.2008.389

M3 - Article

VL - 43

SP - 1

EP - 12

JO - Bone Marrow Transplantation

JF - Bone Marrow Transplantation

SN - 0268-3369

IS - 1

ER -