Soft tissue Rosai-Dorfman disease: Case report

Rubyath C. Rajib, Rajasekharan Pillai, Ibrahim A. Sulaiman, Ibrahim Al-Haddabi

Research output: Contribution to journalArticle

Abstract

Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions.

Original languageEnglish
Pages (from-to)e452-e454
JournalSultan Qaboos University Medical Journal
Volume17
Issue number4
DOIs
Publication statusPublished - Nov 1 2017

Fingerprint

Sinus Histiocytosis
Oman
Cheek
Differential Diagnosis
Outpatients
Immunohistochemistry

Keywords

  • Case report
  • Emperipolesis
  • Histiocytosis
  • Oman
  • Rosai-Dorfman disease
  • S100 proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Soft tissue Rosai-Dorfman disease : Case report. / Rajib, Rubyath C.; Pillai, Rajasekharan; Sulaiman, Ibrahim A.; Al-Haddabi, Ibrahim.

In: Sultan Qaboos University Medical Journal, Vol. 17, No. 4, 01.11.2017, p. e452-e454.

Research output: Contribution to journalArticle

Rajib, Rubyath C. ; Pillai, Rajasekharan ; Sulaiman, Ibrahim A. ; Al-Haddabi, Ibrahim. / Soft tissue Rosai-Dorfman disease : Case report. In: Sultan Qaboos University Medical Journal. 2017 ; Vol. 17, No. 4. pp. e452-e454.
@article{ead8e5980b4546eb9ee28f57cf89d803,
title = "Soft tissue Rosai-Dorfman disease: Case report",
abstract = "Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions.",
keywords = "Case report, Emperipolesis, Histiocytosis, Oman, Rosai-Dorfman disease, S100 proteins",
author = "Rajib, {Rubyath C.} and Rajasekharan Pillai and Sulaiman, {Ibrahim A.} and Ibrahim Al-Haddabi",
year = "2017",
month = "11",
day = "1",
doi = "10.18295/squmj.2017.17.04.012",
language = "English",
volume = "17",
pages = "e452--e454",
journal = "Sultan Qaboos University Medical Journal",
issn = "2075-051X",
publisher = "Sultan Qaboos University",
number = "4",

}

TY - JOUR

T1 - Soft tissue Rosai-Dorfman disease

T2 - Case report

AU - Rajib, Rubyath C.

AU - Pillai, Rajasekharan

AU - Sulaiman, Ibrahim A.

AU - Al-Haddabi, Ibrahim

PY - 2017/11/1

Y1 - 2017/11/1

N2 - Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions.

AB - Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions.

KW - Case report

KW - Emperipolesis

KW - Histiocytosis

KW - Oman

KW - Rosai-Dorfman disease

KW - S100 proteins

UR - http://www.scopus.com/inward/record.url?scp=85040440832&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85040440832&partnerID=8YFLogxK

U2 - 10.18295/squmj.2017.17.04.012

DO - 10.18295/squmj.2017.17.04.012

M3 - Article

AN - SCOPUS:85040440832

VL - 17

SP - e452-e454

JO - Sultan Qaboos University Medical Journal

JF - Sultan Qaboos University Medical Journal

SN - 2075-051X

IS - 4

ER -