TY - JOUR
T1 - Soft tissue Rosai-Dorfman disease
T2 - Case report
AU - Rajib, Rubyath C.
AU - Pillai, Rajasekharan
AU - Sulaiman, Ibrahim A.
AU - Al-Haddabi, Ibrahim
PY - 2017/11
Y1 - 2017/11
N2 - Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions.
AB - Rosai-Dorfman disease (RDD) is a rare benign proliferative histiocytic disorder characterised by massive lymphadenopathy. While extranodal involvement can occur in generalised RDD, isolated soft tissue RDD (STRDD) is extremely rare. We report a 17-year-old male patient who presented to the maxillofacial outpatient department of the Sultan Qaboos Hospital, Salalah, Oman, in 2015 with a painless cheek mass which had been slowly growing over the previous two months. Routine histopathological examinations and immunohistochemistry confirmed a diagnosis of STRDD. Currently, surgical excision is considered to be the most effective curative treatment for STRDD, as the outcomes of other treatment modalities are still unknown. Despite its rarity, STRDD should be considered in the differential diagnosis of histiocytic soft tissue lesions.
KW - Case report
KW - Emperipolesis
KW - Histiocytosis
KW - Oman
KW - Rosai-Dorfman disease
KW - S100 proteins
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U2 - 10.18295/squmj.2017.17.04.012
DO - 10.18295/squmj.2017.17.04.012
M3 - Article
AN - SCOPUS:85040440832
SN - 2075-051X
VL - 17
SP - e452-e454
JO - Sultan Qaboos University Medical Journal
JF - Sultan Qaboos University Medical Journal
IS - 4
ER -