Abstract
Differences in the management of atrial fibrillation (AF) between men and women were investigated by using Gulf SAFE data in the Middle East. The study included 2,043 patients presenting with AF to emergency room (ER) were prospectively enrolled and followed for one-year. Women were older, have higher body mass index (BMI), comorbidities, and health complications than men. With regard to management of AF, cardioversion was recommended more often for men (16.7% vs. 9.3%), and underwent electrical cardioversion (2.2% vs. 1.1%). Women were prescribed digoxin more frequently than men (25.6% vs. 17.4%) and a significant number women received warfarin alone (31.1% vs. 8.7%). No difference between the sexes was noticed in One-year rates of stroke/transient ischemic attacks (TIA) and all-cause of mortality after one-year follow-up (3.1% men vs. 3.3% women, and 7.5% vs. 7.4%). Older age ( 65 years), smoking, alcohol use, CHADS2 scores5 were some of the significant risk factors in men with AF. Suboptimal use of anticoagulants, higher mortality and stroke/TIA events at one year are high but similar between the sexes. ER management revealed high use of rate control strategy and high rate of hospital admission was noticed in women.
| Original language | English |
|---|---|
| Article number | e0175405 |
| Journal | PLoS One |
| Volume | 12 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 1 2017 |
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ASJC Scopus subject areas
- Medicine(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Agricultural and Biological Sciences(all)
Cite this
Sex differences in management and outcomes of patients with atrial fibrillation in the Middle East : Gulf survey of atrial fibrillation events (Gulf SAFE). / Shehab, Abdulla; Zubaid, Mohammad; Bhagavathula, Akshaya Srikanth; Rashed, Wafa A.; Alsheikh-Ali, Alawi A.; AlMahmeed, Wal; Sulaiman, Kadhim; Al-Zakwani, Ibrahim; AlQudaimi, Ahmed; Asaad, Nidal; Amin, Haitham.
In: PLoS One, Vol. 12, No. 5, e0175405, 01.05.2017.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Sex differences in management and outcomes of patients with atrial fibrillation in the Middle East
T2 - Gulf survey of atrial fibrillation events (Gulf SAFE)
AU - Shehab, Abdulla
AU - Zubaid, Mohammad
AU - Bhagavathula, Akshaya Srikanth
AU - Rashed, Wafa A.
AU - Alsheikh-Ali, Alawi A.
AU - AlMahmeed, Wal
AU - Sulaiman, Kadhim
AU - Al-Zakwani, Ibrahim
AU - AlQudaimi, Ahmed
AU - Asaad, Nidal
AU - Amin, Haitham
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Differences in the management of atrial fibrillation (AF) between men and women were investigated by using Gulf SAFE data in the Middle East. The study included 2,043 patients presenting with AF to emergency room (ER) were prospectively enrolled and followed for one-year. Women were older, have higher body mass index (BMI), comorbidities, and health complications than men. With regard to management of AF, cardioversion was recommended more often for men (16.7% vs. 9.3%), and underwent electrical cardioversion (2.2% vs. 1.1%). Women were prescribed digoxin more frequently than men (25.6% vs. 17.4%) and a significant number women received warfarin alone (31.1% vs. 8.7%). No difference between the sexes was noticed in One-year rates of stroke/transient ischemic attacks (TIA) and all-cause of mortality after one-year follow-up (3.1% men vs. 3.3% women, and 7.5% vs. 7.4%). Older age ( 65 years), smoking, alcohol use, CHADS2 scores5 were some of the significant risk factors in men with AF. Suboptimal use of anticoagulants, higher mortality and stroke/TIA events at one year are high but similar between the sexes. ER management revealed high use of rate control strategy and high rate of hospital admission was noticed in women.
AB - Differences in the management of atrial fibrillation (AF) between men and women were investigated by using Gulf SAFE data in the Middle East. The study included 2,043 patients presenting with AF to emergency room (ER) were prospectively enrolled and followed for one-year. Women were older, have higher body mass index (BMI), comorbidities, and health complications than men. With regard to management of AF, cardioversion was recommended more often for men (16.7% vs. 9.3%), and underwent electrical cardioversion (2.2% vs. 1.1%). Women were prescribed digoxin more frequently than men (25.6% vs. 17.4%) and a significant number women received warfarin alone (31.1% vs. 8.7%). No difference between the sexes was noticed in One-year rates of stroke/transient ischemic attacks (TIA) and all-cause of mortality after one-year follow-up (3.1% men vs. 3.3% women, and 7.5% vs. 7.4%). Older age ( 65 years), smoking, alcohol use, CHADS2 scores5 were some of the significant risk factors in men with AF. Suboptimal use of anticoagulants, higher mortality and stroke/TIA events at one year are high but similar between the sexes. ER management revealed high use of rate control strategy and high rate of hospital admission was noticed in women.
UR - http://www.scopus.com/inward/record.url?scp=85019897103&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019897103&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0175405
DO - 10.1371/journal.pone.0175405
M3 - Article
C2 - 28520719
AN - SCOPUS:85019897103
VL - 12
JO - PLoS One
JF - PLoS One
SN - 1932-6203
IS - 5
M1 - e0175405
ER -