TY - JOUR
T1 - Regulation of plasma fatty acid metabolism
AU - Saleh, Jumana
AU - Sniderman, Allan D.
AU - Cianflone, Katherine
N1 - Funding Information:
This work was supported by grants from the Medical Research Council of Canada (KC), Heart and Stroke Foundation of Quebec (KC), and Servier Pharmaceuticals (ADS). KC is a research scholar of the Heart and Stroke Foundation of Canada.
PY - 1999/8
Y1 - 1999/8
N2 - Although adipose tissue serves a crucial function in energy storage, excess adipose tissue - that is, obesity - is often associated with diabetes and cardiovascular disease. A common thread in the weave of complications is increased plasma concentrations of fatty acids. In the present review, we have focused on two specific points that relate to obesity: (i) What are the metabolic consequences of increased free fatty acid concentrations? and (ii) What are the physiological factors that are involved in the regulation of fatty acid uptake or release from adipose tissue? We have tried to emphasize new factors that act as hormones on adipose tissue and in so doing regulate the net concentration of circulating free fatty acids. Copyright (C) 1999 Elsevier Science B.V.
AB - Although adipose tissue serves a crucial function in energy storage, excess adipose tissue - that is, obesity - is often associated with diabetes and cardiovascular disease. A common thread in the weave of complications is increased plasma concentrations of fatty acids. In the present review, we have focused on two specific points that relate to obesity: (i) What are the metabolic consequences of increased free fatty acid concentrations? and (ii) What are the physiological factors that are involved in the regulation of fatty acid uptake or release from adipose tissue? We have tried to emphasize new factors that act as hormones on adipose tissue and in so doing regulate the net concentration of circulating free fatty acids. Copyright (C) 1999 Elsevier Science B.V.
UR - http://www.scopus.com/inward/record.url?scp=0032865063&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032865063&partnerID=8YFLogxK
U2 - 10.1016/S0009-8981(99)00099-6
DO - 10.1016/S0009-8981(99)00099-6
M3 - Article
C2 - 10511290
AN - SCOPUS:0032865063
SN - 0009-8981
VL - 286
SP - 163
EP - 180
JO - Clinica Chimica Acta
JF - Clinica Chimica Acta
IS - 1-2
ER -
