Premature ventricular contractions as a side effect of filgrastim in a child with B-thalassaemia

Hanan F. Nazir; Niranjan Joshi; Yasser A. Wali

doi:10.1017/S1047951117001585

Premature ventricular contractions as a side effect of filgrastim in a child with B-thalassaemia

Hanan F. Nazir^*, Niranjan Joshi, Yasser A. Wali

^*Corresponding author for this work

Child Health

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Premature ventricular contractions are a rare side effect of filgrastim, reported mainly in elderly men. Here we report the case of a 9-year-old child with thalassaemia who developed frequent premature ventricular contractions after three doses of filgrastim were given for deferiprone-induced agranulocytosis. The arrhythmia resolved 3 weeks after discontinuation of filgrastim. Children treated with filgrastim should be carefully monitored for potentially serious arrhythmia.

Original language	English
Pages (from-to)	155-158
Number of pages	4
Journal	Cardiology in the Young
Volume	28
Issue number	1
DOIs	https://doi.org/10.1017/S1047951117001585
Publication status	Published - Jan 1 2018

Keywords

B-thalassaemia
Premature ventricular contractions
agranulocytosis
child
filgrastim

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Cardiology and Cardiovascular Medicine

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10.1017/S1047951117001585

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abstract = "Premature ventricular contractions are a rare side effect of filgrastim, reported mainly in elderly men. Here we report the case of a 9-year-old child with thalassaemia who developed frequent premature ventricular contractions after three doses of filgrastim were given for deferiprone-induced agranulocytosis. The arrhythmia resolved 3 weeks after discontinuation of filgrastim. Children treated with filgrastim should be carefully monitored for potentially serious arrhythmia.",

keywords = "B-thalassaemia, Premature ventricular contractions, agranulocytosis, child, filgrastim",

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AU - Wali, Yasser A.

N1 - Publisher Copyright: © Cambridge University Press 2017.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Premature ventricular contractions are a rare side effect of filgrastim, reported mainly in elderly men. Here we report the case of a 9-year-old child with thalassaemia who developed frequent premature ventricular contractions after three doses of filgrastim were given for deferiprone-induced agranulocytosis. The arrhythmia resolved 3 weeks after discontinuation of filgrastim. Children treated with filgrastim should be carefully monitored for potentially serious arrhythmia.

AB - Premature ventricular contractions are a rare side effect of filgrastim, reported mainly in elderly men. Here we report the case of a 9-year-old child with thalassaemia who developed frequent premature ventricular contractions after three doses of filgrastim were given for deferiprone-induced agranulocytosis. The arrhythmia resolved 3 weeks after discontinuation of filgrastim. Children treated with filgrastim should be carefully monitored for potentially serious arrhythmia.

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KW - filgrastim

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Premature ventricular contractions as a side effect of filgrastim in a child with B-thalassaemia

Abstract

Keywords

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