TY - JOUR
T1 - Potential Therapeutic Benefits of Honey in Neurological Disorders
T2 - The Role of Polyphenols
AU - Iftikhar, Arslan
AU - Nausheen, Rimsha
AU - Muzaffar, Humaira
AU - Naeem, Muhammad Ahsan
AU - Farooq, Muhammad
AU - Khurshid, Mohsin
AU - Almatroudi, Ahmad
AU - Alrumaihi, Faris
AU - Allemailem, Khaled S.
AU - Anwar, Haseeb
N1 - Funding Information:
Acknowledgments: The researchers would like to thank the Deanship of Scientific Research, Qas-sim University for funding the publication of this project.
Funding Information:
The researchers would like to thank the Deanship of Scientific Research, Qassim University for funding the publication of this project.
Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/5/20
Y1 - 2022/5/20
N2 - Honey is the principal premier product of beekeeping familiar to Homo for centuries. In every geological era and culture, evidence can be traced to the potential usefulness of honey in several ailments. With the advent of recent scientific approaches, honey has been proclaimed as a potent complementary and alternative medicine for the management and treatment of several maladies including various neurological disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and multiple sclerosis, etc. In the literature archive, oxidative stress and the deprivation of antioxidants are believed to be the paramount cause of many of these neuropathies. Since different types of honey are abundant with certain antioxidants, primarily in the form of diverse polyphenols, honey is undoubtedly a strong pharmaceutic candidate against multiple neurological diseases. In this review, we have indexed and comprehended the involved mechanisms of various constituent polyphenols including different phenolic acids, flavonoids, and other phytochemicals that manifest multiple antioxidant effects in various neurological disorders. All these mechanistic interpretations of the nutritious components of honey explain and justify the potential recommendation of sweet nectar in ameliorating the burden of neurological disorders that have significantly increased across the world in the last few decades.
AB - Honey is the principal premier product of beekeeping familiar to Homo for centuries. In every geological era and culture, evidence can be traced to the potential usefulness of honey in several ailments. With the advent of recent scientific approaches, honey has been proclaimed as a potent complementary and alternative medicine for the management and treatment of several maladies including various neurological disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and multiple sclerosis, etc. In the literature archive, oxidative stress and the deprivation of antioxidants are believed to be the paramount cause of many of these neuropathies. Since different types of honey are abundant with certain antioxidants, primarily in the form of diverse polyphenols, honey is undoubtedly a strong pharmaceutic candidate against multiple neurological diseases. In this review, we have indexed and comprehended the involved mechanisms of various constituent polyphenols including different phenolic acids, flavonoids, and other phytochemicals that manifest multiple antioxidant effects in various neurological disorders. All these mechanistic interpretations of the nutritious components of honey explain and justify the potential recommendation of sweet nectar in ameliorating the burden of neurological disorders that have significantly increased across the world in the last few decades.
KW - flavonoids
KW - honey
KW - longevity
KW - polyphenols
KW - Flavonoids
KW - Antioxidants/pharmacology
KW - Humans
KW - Honey/analysis
KW - Polyphenols/pharmacology
KW - Alzheimer Disease
UR - https://www.mendeley.com/catalogue/be1868e8-2173-3ee1-9f1c-dffc4c6658f9/
U2 - 10.3390/molecules27103297
DO - 10.3390/molecules27103297
M3 - Article
C2 - 35630774
AN - SCOPUS:85130528052
SN - 1420-3049
VL - 27
JO - Molecules
JF - Molecules
IS - 10
M1 - 3297
ER -