Pattern of viral infections among infants andchildren admitted to the paediatric intensive care unit at Sultan Qaboos University Hospital, Oman

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Abstract

Objectives: The aim of this study was to describe the pattern of viral infections in infants and children admitted to the Paediatric Intensive Care Unit (PICU) at Sultan Qaboos University Hospital (SQUH) in Muscat, Oman.

Methods: A retrospective review of patient records was carried out on all patients admitted to the PICU between January 2011 and December 2012. In order to detect viruses, polymerase chain reaction (PCR) technology was used to detect viruses in nasopharyngeal aspirates, tracheal aspirates, plasma, stool and urine samples. All infants and children below 13 years old, who were admitted to the PICU at SQUH during the study period and with confirmed viral infections, were included in the study.

Results: A total of 373 infants and children were admitted to the PICU during the study period. Viruses were detected in 34 patients. Te most frequently detected viruses were cytomegalovirus (CMV) in 29.4%; this virus was noted predominantly in immuncompromised patients (80%, P = 0.023) and was associated with increased mortality (50%, P = 0.031) and prolonged PICU stay (70%, P = 0.045). Fatalities before discharge were recorded in 23.5% of the patients. Te most frequent risk factors for viral infections were an age of

Conclusion: The results of this study found that CMV was the most common viral infection among infants and children admitted to the PICU in SQUH. CMV was also the leading cause of mortality.

Original languageEnglish
Pages (from-to)e546-e550
JournalSultan Qaboos University Medical Journal
Volume14
Issue number4
Publication statusPublished - Nov 1 2014

Fingerprint

Oman
Pediatric Intensive Care Units
Virus Diseases
Viruses
Cytomegalovirus
Mortality
Sultan
Urine
Technology
Polymerase Chain Reaction

Keywords

  • Children
  • Cytomegalovirus
  • Infants
  • Oman
  • Respiratory syncytial viruses
  • Viral diseases
  • Viruses

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{1956f47f8ca5457581f356e8ac50885a,
title = "Pattern of viral infections among infants andchildren admitted to the paediatric intensive care unit at Sultan Qaboos University Hospital, Oman",
abstract = "Objectives: The aim of this study was to describe the pattern of viral infections in infants and children admitted to the Paediatric Intensive Care Unit (PICU) at Sultan Qaboos University Hospital (SQUH) in Muscat, Oman.Methods: A retrospective review of patient records was carried out on all patients admitted to the PICU between January 2011 and December 2012. In order to detect viruses, polymerase chain reaction (PCR) technology was used to detect viruses in nasopharyngeal aspirates, tracheal aspirates, plasma, stool and urine samples. All infants and children below 13 years old, who were admitted to the PICU at SQUH during the study period and with confirmed viral infections, were included in the study.Results: A total of 373 infants and children were admitted to the PICU during the study period. Viruses were detected in 34 patients. Te most frequently detected viruses were cytomegalovirus (CMV) in 29.4{\%}; this virus was noted predominantly in immuncompromised patients (80{\%}, P = 0.023) and was associated with increased mortality (50{\%}, P = 0.031) and prolonged PICU stay (70{\%}, P = 0.045). Fatalities before discharge were recorded in 23.5{\%} of the patients. Te most frequent risk factors for viral infections were an age of Conclusion: The results of this study found that CMV was the most common viral infection among infants and children admitted to the PICU in SQUH. CMV was also the leading cause of mortality.",
keywords = "Children, Cytomegalovirus, Infants, Oman, Respiratory syncytial viruses, Viral diseases, Viruses",
author = "Abdelmogheth, {Anas Alwogud A} and Al-Nair, {Alddai M A} and Balkhair, {Abdullah A S} and Mahmoud, {Akram M.} and Mohamed El-Naggari",
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T1 - Pattern of viral infections among infants andchildren admitted to the paediatric intensive care unit at Sultan Qaboos University Hospital, Oman

AU - Abdelmogheth, Anas Alwogud A

AU - Al-Nair, Alddai M A

AU - Balkhair, Abdullah A S

AU - Mahmoud, Akram M.

AU - El-Naggari, Mohamed

PY - 2014/11/1

Y1 - 2014/11/1

N2 - Objectives: The aim of this study was to describe the pattern of viral infections in infants and children admitted to the Paediatric Intensive Care Unit (PICU) at Sultan Qaboos University Hospital (SQUH) in Muscat, Oman.Methods: A retrospective review of patient records was carried out on all patients admitted to the PICU between January 2011 and December 2012. In order to detect viruses, polymerase chain reaction (PCR) technology was used to detect viruses in nasopharyngeal aspirates, tracheal aspirates, plasma, stool and urine samples. All infants and children below 13 years old, who were admitted to the PICU at SQUH during the study period and with confirmed viral infections, were included in the study.Results: A total of 373 infants and children were admitted to the PICU during the study period. Viruses were detected in 34 patients. Te most frequently detected viruses were cytomegalovirus (CMV) in 29.4%; this virus was noted predominantly in immuncompromised patients (80%, P = 0.023) and was associated with increased mortality (50%, P = 0.031) and prolonged PICU stay (70%, P = 0.045). Fatalities before discharge were recorded in 23.5% of the patients. Te most frequent risk factors for viral infections were an age of Conclusion: The results of this study found that CMV was the most common viral infection among infants and children admitted to the PICU in SQUH. CMV was also the leading cause of mortality.

AB - Objectives: The aim of this study was to describe the pattern of viral infections in infants and children admitted to the Paediatric Intensive Care Unit (PICU) at Sultan Qaboos University Hospital (SQUH) in Muscat, Oman.Methods: A retrospective review of patient records was carried out on all patients admitted to the PICU between January 2011 and December 2012. In order to detect viruses, polymerase chain reaction (PCR) technology was used to detect viruses in nasopharyngeal aspirates, tracheal aspirates, plasma, stool and urine samples. All infants and children below 13 years old, who were admitted to the PICU at SQUH during the study period and with confirmed viral infections, were included in the study.Results: A total of 373 infants and children were admitted to the PICU during the study period. Viruses were detected in 34 patients. Te most frequently detected viruses were cytomegalovirus (CMV) in 29.4%; this virus was noted predominantly in immuncompromised patients (80%, P = 0.023) and was associated with increased mortality (50%, P = 0.031) and prolonged PICU stay (70%, P = 0.045). Fatalities before discharge were recorded in 23.5% of the patients. Te most frequent risk factors for viral infections were an age of Conclusion: The results of this study found that CMV was the most common viral infection among infants and children admitted to the PICU in SQUH. CMV was also the leading cause of mortality.

KW - Children

KW - Cytomegalovirus

KW - Infants

KW - Oman

KW - Respiratory syncytial viruses

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