Patient specific 3-d modeling of blood flow in a multi-stenosed left coronary artery

Sarfaraz Kamangar*, Irfan Anjum Badruddin, N. Ameer Ahamad, Manzoor Elahi M. Soudagar, Kalimuthu Govindaraju, N. Nik-Ghazali, N. J. Salman Ahmed, T. M. Yunus Khan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The current study investigates the effect of multi stenosis on the hemodynamic parameters such as wall pressure, velocity and wall shear stress in the realistic left coronary artery. Patients CT scan image data of normal and diseased left coronary artery was chosen for the reconstruction of 3D coronary artery models. The diseased 3D model of left coronary artery shows a narrowing of more than 70% and 80% of area stenosis (AS) at the left main stem (LMS) and left circumflex (LCX) respectively. The results show that the decrease in pressure was found downstream to the stenosis as compared to the coronary artery without stenosis. The maximum pressure drop was noted across the 80%Â AS at the left circumflex branch. The recirculation zone was also observed immediate to the stenosis and highest wall shear stress was found across the 80% area stenosis. Our analysis provides an insight into the distribution of wall shear stress and pressure drop, thus improving our understanding on the hemodynamics in realistic coronary artery.

Original languageEnglish
Pages (from-to)257-266
Number of pages10
JournalBio-Medical Materials and Engineering
Volume28
Issue number3
DOIs
Publication statusPublished - 2017

Keywords

  • CFD
  • computer tomography
  • Coronary artery
  • non-Newtonian flow
  • stenosis

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering

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