Abstract
The current study investigates the effect of multi stenosis on the hemodynamic parameters such as wall pressure, velocity and wall shear stress in the realistic left coronary artery. Patients CT scan image data of normal and diseased left coronary artery was chosen for the reconstruction of 3D coronary artery models. The diseased 3D model of left coronary artery shows a narrowing of more than 70% and 80% of area stenosis (AS) at the left main stem (LMS) and left circumflex (LCX) respectively. The results show that the decrease in pressure was found downstream to the stenosis as compared to the coronary artery without stenosis. The maximum pressure drop was noted across the 80%Â AS at the left circumflex branch. The recirculation zone was also observed immediate to the stenosis and highest wall shear stress was found across the 80% area stenosis. Our analysis provides an insight into the distribution of wall shear stress and pressure drop, thus improving our understanding on the hemodynamics in realistic coronary artery.
| Original language | English |
|---|---|
| Pages (from-to) | 257-266 |
| Number of pages | 10 |
| Journal | Bio-Medical Materials and Engineering |
| Volume | 28 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2017 |
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Keywords
- CFD
- computer tomography
- Coronary artery
- non-Newtonian flow
- stenosis
ASJC Scopus subject areas
- Biomaterials
- Biomedical Engineering
Cite this
Patient specific 3-d modeling of blood flow in a multi-stenosed left coronary artery. / Kamangar, Sarfaraz; Badruddin, Irfan Anjum; Ameer Ahamad, N.; Soudagar, Manzoor Elahi M.; Govindaraju, Kalimuthu; Nik-Ghazali, N.; Salman Ahmed, N. J.; Yunus Khan, T. M.
In: Bio-Medical Materials and Engineering, Vol. 28, No. 3, 2017, p. 257-266.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Patient specific 3-d modeling of blood flow in a multi-stenosed left coronary artery
AU - Kamangar, Sarfaraz
AU - Badruddin, Irfan Anjum
AU - Ameer Ahamad, N.
AU - Soudagar, Manzoor Elahi M.
AU - Govindaraju, Kalimuthu
AU - Nik-Ghazali, N.
AU - Salman Ahmed, N. J.
AU - Yunus Khan, T. M.
PY - 2017
Y1 - 2017
N2 - The current study investigates the effect of multi stenosis on the hemodynamic parameters such as wall pressure, velocity and wall shear stress in the realistic left coronary artery. Patients CT scan image data of normal and diseased left coronary artery was chosen for the reconstruction of 3D coronary artery models. The diseased 3D model of left coronary artery shows a narrowing of more than 70% and 80% of area stenosis (AS) at the left main stem (LMS) and left circumflex (LCX) respectively. The results show that the decrease in pressure was found downstream to the stenosis as compared to the coronary artery without stenosis. The maximum pressure drop was noted across the 80%Â AS at the left circumflex branch. The recirculation zone was also observed immediate to the stenosis and highest wall shear stress was found across the 80% area stenosis. Our analysis provides an insight into the distribution of wall shear stress and pressure drop, thus improving our understanding on the hemodynamics in realistic coronary artery.
AB - The current study investigates the effect of multi stenosis on the hemodynamic parameters such as wall pressure, velocity and wall shear stress in the realistic left coronary artery. Patients CT scan image data of normal and diseased left coronary artery was chosen for the reconstruction of 3D coronary artery models. The diseased 3D model of left coronary artery shows a narrowing of more than 70% and 80% of area stenosis (AS) at the left main stem (LMS) and left circumflex (LCX) respectively. The results show that the decrease in pressure was found downstream to the stenosis as compared to the coronary artery without stenosis. The maximum pressure drop was noted across the 80%Â AS at the left circumflex branch. The recirculation zone was also observed immediate to the stenosis and highest wall shear stress was found across the 80% area stenosis. Our analysis provides an insight into the distribution of wall shear stress and pressure drop, thus improving our understanding on the hemodynamics in realistic coronary artery.
KW - CFD
KW - computer tomography
KW - Coronary artery
KW - non-Newtonian flow
KW - stenosis
UR - http://www.scopus.com/inward/record.url?scp=85019912059&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019912059&partnerID=8YFLogxK
U2 - 10.3233/BME-171672
DO - 10.3233/BME-171672
M3 - Article
VL - 28
SP - 257
EP - 266
JO - Bio-Medical Materials and Engineering
JF - Bio-Medical Materials and Engineering
SN - 0959-2989
IS - 3
ER -