Measuring the Effects of Berberine on Serum Prooxidant-Antioxidant Balance in Metabolic Syndrome

Tannaz Jamialahmadi, Paul C Guest, Aida Tasbandi, Khalid Al-Rasadi, Amirhossein Sahebkar

Research output: Contribution to journalArticlepeer-review


Disturbances in the prooxidant-antioxidant balance can occur in metabolic syndrome. Here, we present a protocol for the setup of a clinical trial of metabolic syndrome patients treated with berberine, a dietary phytochemical of the Berberis vulgaris plant, or placebo. The main aim is to obtain a quick and real-time assessment on the overall redox state based on measurement of the prooxidant-antioxidant balance.

Original languageEnglish
Pages (from-to)309-318
Number of pages10
JournalMethods in molecular biology (Clifton, N.J.)
Publication statusPublished - Sep 3 2021


  • Barberry
  • Metabolic syndrome
  • Natural products
  • Prooxidant–antioxidant balance
  • Reactive oxygen species

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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