Lack of effect of chloramphenicol on monoamine, diamine and plasma amine oxidase activities

B. H. Ali

Lack of effect of chloramphenicol on monoamine, diamine and plasma amine oxidase activities

Pharmacology & Clinical Pharmacy

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Abstract

Chloramphenicol treatment in rabbits (60 mg/kg i.m. for 5 days) did not affect significantly (P > 0.1) the activities of monoamine oxidase (MAO) or diamine oxidase (DAO) in liver, heart or brain. Plasma amine oxidase (PAO) was not significantly inhibited (P > 0.1) in goats treated with chloramphenicol (60 mg/kg i.m. for 5 days). Chloramphenicol (2 x 10^-3 mol/l) preincubated with rabbit hepatic MAO had no significant effect (P > 0.1) on the enzyme activity.

Original language	English
Pages (from-to)	193-195
Number of pages	3
Journal	Clinical and Experimental Pharmacology and Physiology
Volume	12
Issue number	2
Publication status	Published - 1985

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ASJC Scopus subject areas

Physiology
Pharmacology (medical)
Pharmacology, Toxicology and Pharmaceutics(all)

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Ali, B. H. (1985). Lack of effect of chloramphenicol on monoamine, diamine and plasma amine oxidase activities. Clinical and Experimental Pharmacology and Physiology, 12(2), 193-195.

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abstract = "Chloramphenicol treatment in rabbits (60 mg/kg i.m. for 5 days) did not affect significantly (P > 0.1) the activities of monoamine oxidase (MAO) or diamine oxidase (DAO) in liver, heart or brain. Plasma amine oxidase (PAO) was not significantly inhibited (P > 0.1) in goats treated with chloramphenicol (60 mg/kg i.m. for 5 days). Chloramphenicol (2 x 10-3 mol/l) preincubated with rabbit hepatic MAO had no significant effect (P > 0.1) on the enzyme activity.",

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AB - Chloramphenicol treatment in rabbits (60 mg/kg i.m. for 5 days) did not affect significantly (P > 0.1) the activities of monoamine oxidase (MAO) or diamine oxidase (DAO) in liver, heart or brain. Plasma amine oxidase (PAO) was not significantly inhibited (P > 0.1) in goats treated with chloramphenicol (60 mg/kg i.m. for 5 days). Chloramphenicol (2 x 10-3 mol/l) preincubated with rabbit hepatic MAO had no significant effect (P > 0.1) on the enzyme activity.

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Lack of effect of chloramphenicol on monoamine, diamine and plasma amine oxidase activities

Abstract

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