LACK OF EFFECT OF CHLORAMPHENICOL ON MONOAMINE, DIAMINE AND PLASMA AMINE OXIDASE ACTIVITIES

B. H. Ali*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

1. Chloramphenicol treatment in rabbits (60 mg/kg i.m. for 5 days) did not affect significantly (P > 0.1) the activities of monoamine oxidase (MAO) or diamine oxidase (DAO) in liver, heart or brain. 2. Plasma amine oxidase (PAO) was not significantly inhibited (P>0.1) in goats treated with chloramphenicol (60 mg/kg i.m. for 5 days). 3. Chloramphenicol (2×10−3 mol/l) preincubated with rabbit hepatic MAO had no significant effect (P>0.1) on the enzyme activity.

Original languageEnglish
Pages (from-to)193-195
Number of pages3
JournalClinical and Experimental Pharmacology and Physiology
Volume12
Issue number2
DOIs
Publication statusPublished - Apr 1985
Externally publishedYes

Keywords

  • chloramphenicol
  • diamine oxidase
  • goats
  • monoamine oxidase
  • plasma amine oxidase
  • rabbits

ASJC Scopus subject areas

  • Physiology
  • Pharmacology
  • Physiology (medical)

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