Lack of correlation between alpha-fetoprotein and tumor size in hepatocellular carcinoma.

S. Sharieff, I. A. Burney, A. Salam, T. Siddiqui

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

OBJECTIVE: To determine whether there was a correlation between tumor size and alpha feto-protein (alpha-FP) levels in hepatocellular carcinoma. SETTING: Retrospective study in tertiary referral center with specialist Oncology services in Southern Pakistan. SUBJECTS: Consecutive patients with biopsy-proven hepatocellular carcinoma diagnosed between January 1994 and June 1998. MAIN OUTCOME MEASURES: Correlation between alpha-FP levels and maximum tumor diameter. RESULTS: The mean tumor size was 8.3 +/- 4.2 cm. The mean alpha-FP level was 17,027 ng/ml. Twenty four percent patients had an alpha-FP level which was within the normal limits (< 10 ng/ml). There was no correlation between tumor size and alpha-FP levels (r = -0.155; p = 0.129). CONCLUSION: There was no correlation between the tumor size and alpha-FP levels.

Original languageEnglish
Pages (from-to)123-124
Number of pages2
JournalJournal of the Pakistan Medical Association
Volume51
Issue number3
Publication statusPublished - Mar 2001

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alpha-Fetoproteins
Hepatocellular Carcinoma
Neoplasms
Proteins
Pakistan
Tertiary Care Centers
Retrospective Studies
Biopsy

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lack of correlation between alpha-fetoprotein and tumor size in hepatocellular carcinoma. / Sharieff, S.; Burney, I. A.; Salam, A.; Siddiqui, T.

In: Journal of the Pakistan Medical Association, Vol. 51, No. 3, 03.2001, p. 123-124.

Research output: Contribution to journalArticle

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AB - OBJECTIVE: To determine whether there was a correlation between tumor size and alpha feto-protein (alpha-FP) levels in hepatocellular carcinoma. SETTING: Retrospective study in tertiary referral center with specialist Oncology services in Southern Pakistan. SUBJECTS: Consecutive patients with biopsy-proven hepatocellular carcinoma diagnosed between January 1994 and June 1998. MAIN OUTCOME MEASURES: Correlation between alpha-FP levels and maximum tumor diameter. RESULTS: The mean tumor size was 8.3 +/- 4.2 cm. The mean alpha-FP level was 17,027 ng/ml. Twenty four percent patients had an alpha-FP level which was within the normal limits (< 10 ng/ml). There was no correlation between tumor size and alpha-FP levels (r = -0.155; p = 0.129). CONCLUSION: There was no correlation between the tumor size and alpha-FP levels.

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