TY - JOUR
T1 - Impaired fasting glucose in Omani adults with no family history of type 2 diabetes
AU - Al-Sinani, Sawsan
AU - Al-Shafaee, Mohammed
AU - Al-Mamari, Ali
AU - Woodhouse, Nicolas
AU - El-Shafe, Omayma
AU - Hassan, Mohammed O.
AU - Al-Yahyaee, Said
AU - Albarwani, Sulayma
AU - Jaju, Deepali
AU - Al-Hashmi, Khamis
AU - Al-Abri, Mohammed
AU - Rizvi, Syed
AU - Bayoumi, Riad
PY - 2014/5
Y1 - 2014/5
N2 - Objectives: Te aim of this study was to estimate the prevalence of impaired fasting glucose (IFG) among Omani adults with no family history (FH) of diabetes and to investigate the factors behind the risk of developing type 2 diabetes (T2D), while excluding a FH of diabetes. Methods: A total of 1,182 Omani adults, aged ≥40 years, visited the Family Medicine & Community Health Clinic at Sultan Qaboos University Hospital, Oman, on days other than the Diabetes Clinic days, from July 2010 to July 2011. Te subjects were interviewed and asked if they had T2D or a FH of T2D. Results: Only 191 (16%) reported no personal history of T2D or FH of the disease. Of these, anthropometric and biochemical data was complete in 159 subjects. Of these a total of 42 (26%) had IFG according to the American Diabetes Association criteria. Body mass index, fasting insulin, haemoglobin A1C and blood pressure (BP), were significantly higher among individuals with IFG (P <0.01, P <0.05, P <0.01 and P <0.01, respectively). In addition, fasting insulin, BP and serum lipid profile were correlated with obesity indices (P <0.05). Obesity indices were strongly associated with the risk of IFG among Omanis, with waist circumference being the strongest predictor. Conclusion: Despite claiming no FH of diabetes, a large number of Omani adults in this study had a high risk of developing diabetes. This is possibly due to environmental factors and endogamy. Te high prevalence of obesity combined with genetically susceptible individuals is a warning that diabetes could be a future epidemic in Oman.
AB - Objectives: Te aim of this study was to estimate the prevalence of impaired fasting glucose (IFG) among Omani adults with no family history (FH) of diabetes and to investigate the factors behind the risk of developing type 2 diabetes (T2D), while excluding a FH of diabetes. Methods: A total of 1,182 Omani adults, aged ≥40 years, visited the Family Medicine & Community Health Clinic at Sultan Qaboos University Hospital, Oman, on days other than the Diabetes Clinic days, from July 2010 to July 2011. Te subjects were interviewed and asked if they had T2D or a FH of T2D. Results: Only 191 (16%) reported no personal history of T2D or FH of the disease. Of these, anthropometric and biochemical data was complete in 159 subjects. Of these a total of 42 (26%) had IFG according to the American Diabetes Association criteria. Body mass index, fasting insulin, haemoglobin A1C and blood pressure (BP), were significantly higher among individuals with IFG (P <0.01, P <0.05, P <0.01 and P <0.01, respectively). In addition, fasting insulin, BP and serum lipid profile were correlated with obesity indices (P <0.05). Obesity indices were strongly associated with the risk of IFG among Omanis, with waist circumference being the strongest predictor. Conclusion: Despite claiming no FH of diabetes, a large number of Omani adults in this study had a high risk of developing diabetes. This is possibly due to environmental factors and endogamy. Te high prevalence of obesity combined with genetically susceptible individuals is a warning that diabetes could be a future epidemic in Oman.
KW - Diabetes mellitus
KW - Obesity
KW - Oman
KW - Prediabetic state
KW - Prevalence
KW - Type 2
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M3 - Article
AN - SCOPUS:84899695586
SN - 2075-051X
VL - 14
SP - e183-e189
JO - Sultan Qaboos University Medical Journal
JF - Sultan Qaboos University Medical Journal
IS - 2
ER -