Genetic susceptibility in Dupuytren's disease: Lack of association of a novel transforming growth factor β 2 polymorphism in Dupuytren's disease

A. Bayat, A. Alansar, A. H. Hajeer, M. Shah, J. S. Watson, J. K. Stanley, M. W.J. Ferguson, W. E.R. Ollier

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22 Citations (Scopus)


The genes involved in the pathogenesis of Dupuytren's disease have yet to be identified. In this study, we tested for an association between Dupuytren's disease (DD) and a novel insertion polymorphism within the 5′-untranslated region (5′-UTR), of the TGFβ 2 gene. DNA samples from 179 DD patients and 187 ethnically matched controls were examined. There was no statistically significant difference in TGFβ 2 allele frequency distributions between cases and controls for the TGFβ 2 polymorphism.

Original languageEnglish
Pages (from-to)47-49
Number of pages3
JournalJournal of Hand Surgery
Volume27 B
Issue number1
Publication statusPublished - 2002


ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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