Genetic susceptibility in Dupuytren's disease: Lack of association of a novel transforming growth factor β 2 polymorphism in Dupuytren's disease

A. Bayat; A. Alansar; A. H. Hajeer; M. Shah; J. S. Watson; J. K. Stanley; M. W.J. Ferguson; W. E.R. Ollier

doi:10.1054/jhsb.2001.0689

Genetic susceptibility in Dupuytren's disease: Lack of association of a novel transforming growth factor β ₂ polymorphism in Dupuytren's disease

A. Bayat^*, A. Alansar, A. H. Hajeer, M. Shah, J. S. Watson, J. K. Stanley, M. W.J. Ferguson, W. E.R. Ollier

^*Corresponding author for this work

Biology

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

The genes involved in the pathogenesis of Dupuytren's disease have yet to be identified. In this study, we tested for an association between Dupuytren's disease (DD) and a novel insertion polymorphism within the 5′-untranslated region (5′-UTR), of the TGFβ ₂ gene. DNA samples from 179 DD patients and 187 ethnically matched controls were examined. There was no statistically significant difference in TGFβ ₂ allele frequency distributions between cases and controls for the TGFβ ₂ polymorphism.

Original language	English
Pages (from-to)	47-49
Number of pages	3
Journal	Journal of Hand Surgery
Volume	27 B
Issue number	1
DOIs	https://doi.org/10.1054/jhsb.2001.0689
Publication status	Published - 2002

ASJC Scopus subject areas

Surgery
Orthopedics and Sports Medicine

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Genetic susceptibility in Dupuytren's disease : Lack of association of a novel transforming growth factor β ₂ polymorphism in Dupuytren's disease. / Bayat, A.; Alansar, A.; Hajeer, A. H.; Shah, M.; Watson, J. S.; Stanley, J. K.; Ferguson, M. W.J.; Ollier, W. E.R.

In: Journal of Hand Surgery, Vol. 27 B, No. 1, 2002, p. 47-49.

Research output: Contribution to journal › Article › peer-review

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