Abstract
The genes involved in the pathogenesis of Dupuytren's disease have yet to be identified. In this study, we tested for an association between Dupuytren's disease (DD) and a novel insertion polymorphism within the 5′-untranslated region (5′-UTR), of the TGFβ 2 gene. DNA samples from 179 DD patients and 187 ethnically matched controls were examined. There was no statistically significant difference in TGFβ 2 allele frequency distributions between cases and controls for the TGFβ 2 polymorphism.
| Original language | English |
|---|---|
| Pages (from-to) | 47-49 |
| Number of pages | 3 |
| Journal | Journal of Hand Surgery |
| Volume | 27 B |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2002 |
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ASJC Scopus subject areas
- Surgery
- Orthopedics and Sports Medicine
Cite this
Genetic susceptibility in Dupuytren's disease : Lack of association of a novel transforming growth factor β 2 polymorphism in Dupuytren's disease. / Bayat, A.; Alansar, A.; Hajeer, A. H.; Shah, M.; Watson, J. S.; Stanley, J. K.; Ferguson, M. W.J.; Ollier, W. E.R.
In: Journal of Hand Surgery, Vol. 27 B, No. 1, 2002, p. 47-49.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Genetic susceptibility in Dupuytren's disease
T2 - Lack of association of a novel transforming growth factor β 2 polymorphism in Dupuytren's disease
AU - Bayat, A.
AU - Alansar, A.
AU - Hajeer, A. H.
AU - Shah, M.
AU - Watson, J. S.
AU - Stanley, J. K.
AU - Ferguson, M. W.J.
AU - Ollier, W. E.R.
PY - 2002
Y1 - 2002
N2 - The genes involved in the pathogenesis of Dupuytren's disease have yet to be identified. In this study, we tested for an association between Dupuytren's disease (DD) and a novel insertion polymorphism within the 5′-untranslated region (5′-UTR), of the TGFβ 2 gene. DNA samples from 179 DD patients and 187 ethnically matched controls were examined. There was no statistically significant difference in TGFβ 2 allele frequency distributions between cases and controls for the TGFβ 2 polymorphism.
AB - The genes involved in the pathogenesis of Dupuytren's disease have yet to be identified. In this study, we tested for an association between Dupuytren's disease (DD) and a novel insertion polymorphism within the 5′-untranslated region (5′-UTR), of the TGFβ 2 gene. DNA samples from 179 DD patients and 187 ethnically matched controls were examined. There was no statistically significant difference in TGFβ 2 allele frequency distributions between cases and controls for the TGFβ 2 polymorphism.
UR - http://www.scopus.com/inward/record.url?scp=0036205665&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036205665&partnerID=8YFLogxK
U2 - 10.1054/jhsb.2001.0689
DO - 10.1054/jhsb.2001.0689
M3 - Article
C2 - 11895345
AN - SCOPUS:0036205665
VL - 27 B
SP - 47
EP - 49
JO - The Hand
JF - The Hand
SN - 0266-7681
IS - 1
ER -