Abstract
The genes involved in the pathogenesis of Dupuytren's disease have yet to be identified. In this study, we tested for an association between Dupuytren's disease (DD) and a novel insertion polymorphism within the 5′-untranslated region (5′-UTR), of the TGFβ 2 gene. DNA samples from 179 DD patients and 187 ethnically matched controls were examined. There was no statistically significant difference in TGFβ 2 allele frequency distributions between cases and controls for the TGFβ 2 polymorphism.
| Original language | English |
|---|---|
| Pages (from-to) | 47-49 |
| Number of pages | 3 |
| Journal | Journal of Hand Surgery |
| Volume | 27 B |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2002 |
ASJC Scopus subject areas
- Surgery
- Orthopedics and Sports Medicine
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Bayat, A., Alansar, A., Hajeer, A. H., Shah, M., Watson, J. S., Stanley, J. K., Ferguson, M. W. J., & Ollier, W. E. R. (2002). Genetic susceptibility in Dupuytren's disease: Lack of association of a novel transforming growth factor β 2 polymorphism in Dupuytren's disease. Journal of Hand Surgery, 27 B(1), 47-49. https://doi.org/10.1054/jhsb.2001.0689