Abstract
Fluoxetine is a selective serotonin re-uptake inhibitor used to treat anxiety and depression in humans. It has been detected as a contaminant in the surface waters in many countries. The effects of fluoxetine (0, 0.03, 0.3, and 3 μg L−1) on the swimming and behavioral responses of Bufo arabicus tadpoles to alarm chemicals from predatory dragonfly larvae (Anax imperator) were measured. Fluoxetine significantly reduced swimming speed at 0.3 and 3 μg L−1in the absence of predator alarm chemicals but had no effect in their presence. Tadpoles exposed to predator alarm chemicals avoided open water and preferred to hide. Exposure to fluoxetine at 3 μg L−1completely eliminated this predator avoidance response, making the tadpoles more vulnerable to predation.
| Original language | English |
|---|---|
| Pages (from-to) | 641-649 |
| Number of pages | 9 |
| Journal | Toxicological and Environmental Chemistry |
| Volume | 96 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 21 2014 |
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Keywords
- Bufo arabicus tadpole
- fluoxetine 5-HT
- predator
ASJC Scopus subject areas
- Environmental Chemistry
- Health, Toxicology and Mutagenesis
- Pollution
Cite this
Fluoxetine inhibits predator avoidance behavior in tadpoles. / Barry, Michael J.
In: Toxicological and Environmental Chemistry, Vol. 96, No. 4, 21.04.2014, p. 641-649.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Fluoxetine inhibits predator avoidance behavior in tadpoles
AU - Barry, Michael J.
PY - 2014/4/21
Y1 - 2014/4/21
N2 - Fluoxetine is a selective serotonin re-uptake inhibitor used to treat anxiety and depression in humans. It has been detected as a contaminant in the surface waters in many countries. The effects of fluoxetine (0, 0.03, 0.3, and 3 μg L−1) on the swimming and behavioral responses of Bufo arabicus tadpoles to alarm chemicals from predatory dragonfly larvae (Anax imperator) were measured. Fluoxetine significantly reduced swimming speed at 0.3 and 3 μg L−1in the absence of predator alarm chemicals but had no effect in their presence. Tadpoles exposed to predator alarm chemicals avoided open water and preferred to hide. Exposure to fluoxetine at 3 μg L−1completely eliminated this predator avoidance response, making the tadpoles more vulnerable to predation.
AB - Fluoxetine is a selective serotonin re-uptake inhibitor used to treat anxiety and depression in humans. It has been detected as a contaminant in the surface waters in many countries. The effects of fluoxetine (0, 0.03, 0.3, and 3 μg L−1) on the swimming and behavioral responses of Bufo arabicus tadpoles to alarm chemicals from predatory dragonfly larvae (Anax imperator) were measured. Fluoxetine significantly reduced swimming speed at 0.3 and 3 μg L−1in the absence of predator alarm chemicals but had no effect in their presence. Tadpoles exposed to predator alarm chemicals avoided open water and preferred to hide. Exposure to fluoxetine at 3 μg L−1completely eliminated this predator avoidance response, making the tadpoles more vulnerable to predation.
KW - Bufo arabicus tadpole
KW - fluoxetine 5-HT
KW - predator
UR - http://www.scopus.com/inward/record.url?scp=84912017022&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84912017022&partnerID=8YFLogxK
U2 - 10.1080/02772248.2014.966713
DO - 10.1080/02772248.2014.966713
M3 - Article
VL - 96
SP - 641
EP - 649
JO - Toxicological and Environmental Chemistry
JF - Toxicological and Environmental Chemistry
SN - 0277-2248
IS - 4
ER -