Before embarking on a new crop such as medicinal herb production, growers want to know what to expect in terms of plant survival, yield of tops and roots, and whether any significant insect pests or diseases are present. These screening trials have been conducted over three years on between 2 and 4 sites ranging from eastern to western Kansas to address these questions. Of the 5 annuals and 27 perennials screened so far, 18 were rated as "good" potential based on survival, vigor ratings and yield. Another 10 were rated as "medium," and had some limitations which might be overcome through improved cultural methods or varieties. Four species were rated as "poor" due lack of survival, severe insect or disease pest problems, winter survival, and/or lack of vigor under transplanted conditions. One of these, Echinacea angustifolia, might be improved through direct seeding, but other problems such as weed control are encountered in a direct seeding system.