Epidemiological features of aplastic anaemia in Pakistan

S. N. Adil, I. A. Burney, G. N. Kakepoto, M. Khurshid

Research output: Contribution to journalArticle

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Abstract

Objective: To complete the data on the demographic features of patients diagnosed to have aplastic anemia at a single institution over a 7.5 years period. Methods: Demographic information was retrieved from the patients medical records retrospectively as well as prospectively of those patients who presented with features of aplastic anaemia. Their diagnosis was confirmed by performing a complete blood count and bone marrow trephine. Results: One hundred and forty four patients were diagnosed to have aplastic anemia; there were 106 males and 38 females. Their ages ranged from 2 to 75 years, with a median of 17 years, 112 (77.7%) patients were below the age of 30 years. Severe aplastic anemia (SAA) was seen in 74 (51.4%), very severe (VSAA) in 24 (16.7%) and non-severe aplastic anemia (NSAA) in 46 (31.9%) patients. No obvious cause could be established for 74.3%. Thirteen patients admitted using drugs known to cause AA and one was a radiographer (9%). Out of 44 patients tested, 7 (15.9%) were found to have either hepatitis B virus markers or antibody to hepatitis C at the time of diagnosis of AA. However it was difficult to establish a cause and effect relationship with either drugs or viruses. Conclusion: Aplastic anaemia is found to occur mostly in young males. The most common type was idiopathic severe aplastic anaemia.

Original languageEnglish
Pages (from-to)443-445
Number of pages3
JournalJournal of the Pakistan Medical Association
Volume51
Issue number12
Publication statusPublished - Dec 2001

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Aplastic Anemia
Pakistan
Demography
Hepatitis B Antibodies
Blood Cell Count
Hepatitis C
Hepatitis B virus
Pharmaceutical Preparations
Medical Records
Bone Marrow
Viruses

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Epidemiological features of aplastic anaemia in Pakistan. / Adil, S. N.; Burney, I. A.; Kakepoto, G. N.; Khurshid, M.

In: Journal of the Pakistan Medical Association, Vol. 51, No. 12, 12.2001, p. 443-445.

Research output: Contribution to journalArticle

Adil, SN, Burney, IA, Kakepoto, GN & Khurshid, M 2001, 'Epidemiological features of aplastic anaemia in Pakistan', Journal of the Pakistan Medical Association, vol. 51, no. 12, pp. 443-445.
Adil, S. N. ; Burney, I. A. ; Kakepoto, G. N. ; Khurshid, M. / Epidemiological features of aplastic anaemia in Pakistan. In: Journal of the Pakistan Medical Association. 2001 ; Vol. 51, No. 12. pp. 443-445.
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