TY - JOUR
T1 - Effects of multimodal training program on muscle deoxygenation in women with breast cancer: A randomized controlled trial.
T2 - A randomized controlled trial
AU - Hiraoui, Mouadh
AU - Gmada, Nabil
AU - Al-Hadabi, Badria
AU - Mezlini, Amel
AU - Al Busafi, Majid
AU - Doutrellot, Pierre Louis
AU - Bouhlel, Ezdine
AU - Ahmaidi, Said
N1 - Publisher Copyright:
© 2022 Akadémiai Kiadó, Budapest.
PY - 2022/6/7
Y1 - 2022/6/7
N2 - PURPOSE: Chemotherapy and/or radiation are the most often delivered treatments to cancer patients. Usually during the adjuvant treatment, patients complain about fatigue. In addition, physical exercise during adjuvant treatment of cancer seems to have beneficial effects. The aim of this investigation was to assess the effects of multimodal aerobic and strength exercises programs on muscle deoxygenation of patients with breast cancer undergoing adjuvant chemotherapy treatment.METHODS: Thirty-two women with breast cancer (20 patients as the training group and 12 patients as the control group) undergoing adjuvant chemotherapy participated in the study. The training group took part in 6 weeks of supervised intermittent aerobic cycling, home-based walking, isometric and electrical muscle stimulation (EMS) exercise training programs. The Outcome measures were muscle deoxygenation (ΔHHb), Maximal Voluntary isometric Contraction (MViC) and Endurance Time (ET) before and after the training period.RESULTS: Compared to the control group, a significant increase in ΔHHb (P < 0.01) accompanied with an increase in ET (P < 0.01) and MViC (P < 0.01) of the quadriceps was obtained in the training group. However, no significant differences of MViC, ET and ΔHHb were observed in the control group.CONCLUSION: Multimodal aerobic and strength exercise programs enhance muscle oxygen utilization, which may partly explain the improvement in muscular strength and endurance, and the reduction of muscle fatigue in patients with breast cancer during an adjuvant chemotherapy period.
AB - PURPOSE: Chemotherapy and/or radiation are the most often delivered treatments to cancer patients. Usually during the adjuvant treatment, patients complain about fatigue. In addition, physical exercise during adjuvant treatment of cancer seems to have beneficial effects. The aim of this investigation was to assess the effects of multimodal aerobic and strength exercises programs on muscle deoxygenation of patients with breast cancer undergoing adjuvant chemotherapy treatment.METHODS: Thirty-two women with breast cancer (20 patients as the training group and 12 patients as the control group) undergoing adjuvant chemotherapy participated in the study. The training group took part in 6 weeks of supervised intermittent aerobic cycling, home-based walking, isometric and electrical muscle stimulation (EMS) exercise training programs. The Outcome measures were muscle deoxygenation (ΔHHb), Maximal Voluntary isometric Contraction (MViC) and Endurance Time (ET) before and after the training period.RESULTS: Compared to the control group, a significant increase in ΔHHb (P < 0.01) accompanied with an increase in ET (P < 0.01) and MViC (P < 0.01) of the quadriceps was obtained in the training group. However, no significant differences of MViC, ET and ΔHHb were observed in the control group.CONCLUSION: Multimodal aerobic and strength exercise programs enhance muscle oxygen utilization, which may partly explain the improvement in muscular strength and endurance, and the reduction of muscle fatigue in patients with breast cancer during an adjuvant chemotherapy period.
KW - breast cancer
KW - multimodal training
KW - muscle deoxygenation
KW - muscle fatigue
KW - strength exercise
KW - Humans
KW - Muscle Strength/physiology
KW - Muscles
KW - Exercise Therapy
KW - Resistance Training
KW - Female
KW - Chemotherapy, Adjuvant
KW - Breast Neoplasms/therapy
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UR - http://www.scopus.com/inward/citedby.url?scp=85135373905&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/bb861c4a-2041-341b-b6ee-9ff93ea9602b/
U2 - 10.1556/2060.2022.00148
DO - 10.1556/2060.2022.00148
M3 - Article
C2 - 35895571
AN - SCOPUS:85135373905
SN - 2498-602X
VL - 109
SP - 246
EP - 260
JO - Physiology International
JF - Physiology International
IS - 2
M1 - 109(2)
ER -
