TY - JOUR
T1 - Effect of amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients
AU - Akhtar, Muhammad Shoaib
AU - Ramzan, Ayesha
AU - Ali, Amanat
AU - Ahmad, Maqsood
PY - 2011/9
Y1 - 2011/9
N2 - The present study evaluated the anti-hyperglycemic and lipid-lowering properties of Emblica officinalis Gaertn. fruit in normal and diabetic human volunteers. The results indicated a significant decrease (P < 0.05) in fasting and 2-h post-prandial blood glucose levels on the 21st day in both normal and diabetic subjects receiving 1, 2 or 3 g E. officinalis powder per day as compared with their baseline values. Significant (P < 0.05) decreases were also observed in total cholesterol and triglycerides in both normal and diabetic volunteers on day 21 that were given either 2 or 3 g E. officinalis powder per day. However, diabetic volunteers receiving only 3 g E. officinalis powder exhibited a significant (P < 0.05) decrease in total lipids on day 21. Both normal and diabetic volunteers receiving 2 or 3 g E. officinalis powder significantly (P < 0.05) improved high-density lipoprotein-cholesterol and lowered low-density lipoprotein-cholesterol levels.
AB - The present study evaluated the anti-hyperglycemic and lipid-lowering properties of Emblica officinalis Gaertn. fruit in normal and diabetic human volunteers. The results indicated a significant decrease (P < 0.05) in fasting and 2-h post-prandial blood glucose levels on the 21st day in both normal and diabetic subjects receiving 1, 2 or 3 g E. officinalis powder per day as compared with their baseline values. Significant (P < 0.05) decreases were also observed in total cholesterol and triglycerides in both normal and diabetic volunteers on day 21 that were given either 2 or 3 g E. officinalis powder per day. However, diabetic volunteers receiving only 3 g E. officinalis powder exhibited a significant (P < 0.05) decrease in total lipids on day 21. Both normal and diabetic volunteers receiving 2 or 3 g E. officinalis powder significantly (P < 0.05) improved high-density lipoprotein-cholesterol and lowered low-density lipoprotein-cholesterol levels.
KW - Amla fruit
KW - Emblica officinalis Gaertn.
KW - blood glucose
KW - lipid profile
KW - normal and diabetic human volunteers
UR - http://www.scopus.com/inward/record.url?scp=79961201714&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79961201714&partnerID=8YFLogxK
U2 - 10.3109/09637486.2011.560565
DO - 10.3109/09637486.2011.560565
M3 - Article
C2 - 21495900
AN - SCOPUS:79961201714
SN - 0963-7486
VL - 62
SP - 609
EP - 616
JO - International Journal of Food Sciences and Nutrition
JF - International Journal of Food Sciences and Nutrition
IS - 6
ER -
