Diagnostic dilemmas in intraductal papillomas of the breast - Experience at Sultan Qaboos university hospital in the Sultanate of Oman

Adil Aljarrah, Kamran Ahmad Malik, Husam Jamil, Zoheb Jaffer, Sukhpal Sawhney, Ritu Lakhtakia

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objectives: The aim of this retrospective study was to correlate the significance and accuracy of the colour of nipple discharge and breast ultrasound imaging in the diagnosis of intraductal papilloma. Methods: This is a retrospective study of 34 patients who underwent 36 microdochectomies in Sultan Qaboos University Hospital (SQUH) in the Sultanate of Oman, over a 4 year period of January 2009 till December 2012. The confounders considered were patient age, physical examination findings, nipple discharge cytology result, ultrasound results and biopsy report following microdochectomy. Comparisons analysis, charts and graphs were made using the SPSS software (version 20). Results: The mean age of the patients was 44(27-73) years old. Twenty-seven out 36 (75%) patients had presented with nipple discharge, 14 out 27 (52%) had blood stained nipple discharge and 13(48%) with coloured discharge (yellow, brown and green), 9 patients had no discharge. The final histopathology showed intraductal papilloma 13 (36%), duct ectasia 18(50%), DCIS 1 (2.7%), fibrocystic disease 3(8.3%) and LCIS 1(2.7%). Thirteen out of 36 had intraductal papilloma on final histopathology. The correlation between blood stained discharge and final histopathology of intraductal papilloma was insignificant (p=0.44). Conclusion: Nipple discharge is irrelevant to the diagnosis of intraductal papilloma. Spontaneous nipple discharge regardless of color is to be referred to breast surgeon and to be assessed with triple assessment. Surgery remains the mainstay of treatment.

Original languageEnglish
Pages (from-to)431-434
Number of pages4
JournalPakistan Journal of Medical Sciences
Volume31
Issue number2
DOIs
Publication statusPublished - Mar 1 2015

Fingerprint

Intraductal Papilloma
Oman
Breast
Retrospective Studies
Color
Pathologic Dilatations
Carcinoma, Intraductal, Noninfiltrating
Physical Examination
Cell Biology
Sultan
Nipple Discharge
Ultrasonography
Software
Biopsy

Keywords

  • Breast Intraductal Papilloma
  • Duct Ectasia
  • Ductal Carcinoma In Situ (DCIS)
  • Lobular Carcinoma In Situ LCIS
  • Microdochectomy
  • Nipple Discharge

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Diagnostic dilemmas in intraductal papillomas of the breast - Experience at Sultan Qaboos university hospital in the Sultanate of Oman. / Aljarrah, Adil; Malik, Kamran Ahmad; Jamil, Husam; Jaffer, Zoheb; Sawhney, Sukhpal; Lakhtakia, Ritu.

In: Pakistan Journal of Medical Sciences, Vol. 31, No. 2, 01.03.2015, p. 431-434.

Research output: Contribution to journalArticle

Aljarrah, Adil ; Malik, Kamran Ahmad ; Jamil, Husam ; Jaffer, Zoheb ; Sawhney, Sukhpal ; Lakhtakia, Ritu. / Diagnostic dilemmas in intraductal papillomas of the breast - Experience at Sultan Qaboos university hospital in the Sultanate of Oman. In: Pakistan Journal of Medical Sciences. 2015 ; Vol. 31, No. 2. pp. 431-434.
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abstract = "Objectives: The aim of this retrospective study was to correlate the significance and accuracy of the colour of nipple discharge and breast ultrasound imaging in the diagnosis of intraductal papilloma. Methods: This is a retrospective study of 34 patients who underwent 36 microdochectomies in Sultan Qaboos University Hospital (SQUH) in the Sultanate of Oman, over a 4 year period of January 2009 till December 2012. The confounders considered were patient age, physical examination findings, nipple discharge cytology result, ultrasound results and biopsy report following microdochectomy. Comparisons analysis, charts and graphs were made using the SPSS software (version 20). Results: The mean age of the patients was 44(27-73) years old. Twenty-seven out 36 (75{\%}) patients had presented with nipple discharge, 14 out 27 (52{\%}) had blood stained nipple discharge and 13(48{\%}) with coloured discharge (yellow, brown and green), 9 patients had no discharge. The final histopathology showed intraductal papilloma 13 (36{\%}), duct ectasia 18(50{\%}), DCIS 1 (2.7{\%}), fibrocystic disease 3(8.3{\%}) and LCIS 1(2.7{\%}). Thirteen out of 36 had intraductal papilloma on final histopathology. The correlation between blood stained discharge and final histopathology of intraductal papilloma was insignificant (p=0.44). Conclusion: Nipple discharge is irrelevant to the diagnosis of intraductal papilloma. Spontaneous nipple discharge regardless of color is to be referred to breast surgeon and to be assessed with triple assessment. Surgery remains the mainstay of treatment.",
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AU - Malik, Kamran Ahmad

AU - Jamil, Husam

AU - Jaffer, Zoheb

AU - Sawhney, Sukhpal

AU - Lakhtakia, Ritu

PY - 2015/3/1

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N2 - Objectives: The aim of this retrospective study was to correlate the significance and accuracy of the colour of nipple discharge and breast ultrasound imaging in the diagnosis of intraductal papilloma. Methods: This is a retrospective study of 34 patients who underwent 36 microdochectomies in Sultan Qaboos University Hospital (SQUH) in the Sultanate of Oman, over a 4 year period of January 2009 till December 2012. The confounders considered were patient age, physical examination findings, nipple discharge cytology result, ultrasound results and biopsy report following microdochectomy. Comparisons analysis, charts and graphs were made using the SPSS software (version 20). Results: The mean age of the patients was 44(27-73) years old. Twenty-seven out 36 (75%) patients had presented with nipple discharge, 14 out 27 (52%) had blood stained nipple discharge and 13(48%) with coloured discharge (yellow, brown and green), 9 patients had no discharge. The final histopathology showed intraductal papilloma 13 (36%), duct ectasia 18(50%), DCIS 1 (2.7%), fibrocystic disease 3(8.3%) and LCIS 1(2.7%). Thirteen out of 36 had intraductal papilloma on final histopathology. The correlation between blood stained discharge and final histopathology of intraductal papilloma was insignificant (p=0.44). Conclusion: Nipple discharge is irrelevant to the diagnosis of intraductal papilloma. Spontaneous nipple discharge regardless of color is to be referred to breast surgeon and to be assessed with triple assessment. Surgery remains the mainstay of treatment.

AB - Objectives: The aim of this retrospective study was to correlate the significance and accuracy of the colour of nipple discharge and breast ultrasound imaging in the diagnosis of intraductal papilloma. Methods: This is a retrospective study of 34 patients who underwent 36 microdochectomies in Sultan Qaboos University Hospital (SQUH) in the Sultanate of Oman, over a 4 year period of January 2009 till December 2012. The confounders considered were patient age, physical examination findings, nipple discharge cytology result, ultrasound results and biopsy report following microdochectomy. Comparisons analysis, charts and graphs were made using the SPSS software (version 20). Results: The mean age of the patients was 44(27-73) years old. Twenty-seven out 36 (75%) patients had presented with nipple discharge, 14 out 27 (52%) had blood stained nipple discharge and 13(48%) with coloured discharge (yellow, brown and green), 9 patients had no discharge. The final histopathology showed intraductal papilloma 13 (36%), duct ectasia 18(50%), DCIS 1 (2.7%), fibrocystic disease 3(8.3%) and LCIS 1(2.7%). Thirteen out of 36 had intraductal papilloma on final histopathology. The correlation between blood stained discharge and final histopathology of intraductal papilloma was insignificant (p=0.44). Conclusion: Nipple discharge is irrelevant to the diagnosis of intraductal papilloma. Spontaneous nipple discharge regardless of color is to be referred to breast surgeon and to be assessed with triple assessment. Surgery remains the mainstay of treatment.

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KW - Duct Ectasia

KW - Ductal Carcinoma In Situ (DCIS)

KW - Lobular Carcinoma In Situ LCIS

KW - Microdochectomy

KW - Nipple Discharge

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