Colonic adenocarcinoma in a rhesus macaque (Macaca mulatta)

Eugene H. Johnson; Susan E. Morgenstern; Jill M. Perham; Stephen W. Barthold

Colonic adenocarcinoma in a rhesus macaque (Macaca mulatta)

Eugene H. Johnson^*, Susan E. Morgenstern, Jill M. Perham, Stephen W. Barthold

^*Corresponding author for this work

Animal and Veterinary Sciences

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A spontaneous colonic adenocarcinoma and endometriosis was diagnosed in a 34-year-old female rhesus macaque (Macaca mulatta). The tumor caused partial obstruction of the ascending colon and histologically resembled the commonly described napkin-ring tumors of the descending and sigmoid colon found in humans. Serum levels of CA 125, a high-molecular-weight glycoprotein antigen that has been reported elevated in a variety of pathological conditions of the pelvic cavity in humans, was severely elevated. Both the adenocarcinoma and the endometriosis may have contributed to this finding.

Original language	English
Pages (from-to)	435-438
Number of pages	4
Journal	Journal of Medical Primatology
Volume	25
Issue number	6
Publication status	Published - Dec 1996

Keywords

CA-125
Colonic adenocarcinoma
Endometriosis
Rhesus macaque

ASJC Scopus subject areas

Animal Science and Zoology
veterinary(all)

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abstract = "A spontaneous colonic adenocarcinoma and endometriosis was diagnosed in a 34-year-old female rhesus macaque (Macaca mulatta). The tumor caused partial obstruction of the ascending colon and histologically resembled the commonly described napkin-ring tumors of the descending and sigmoid colon found in humans. Serum levels of CA 125, a high-molecular-weight glycoprotein antigen that has been reported elevated in a variety of pathological conditions of the pelvic cavity in humans, was severely elevated. Both the adenocarcinoma and the endometriosis may have contributed to this finding.",

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AU - Johnson, Eugene H.

AU - Morgenstern, Susan E.

AU - Perham, Jill M.

AU - Barthold, Stephen W.

PY - 1996/12

Y1 - 1996/12

N2 - A spontaneous colonic adenocarcinoma and endometriosis was diagnosed in a 34-year-old female rhesus macaque (Macaca mulatta). The tumor caused partial obstruction of the ascending colon and histologically resembled the commonly described napkin-ring tumors of the descending and sigmoid colon found in humans. Serum levels of CA 125, a high-molecular-weight glycoprotein antigen that has been reported elevated in a variety of pathological conditions of the pelvic cavity in humans, was severely elevated. Both the adenocarcinoma and the endometriosis may have contributed to this finding.

AB - A spontaneous colonic adenocarcinoma and endometriosis was diagnosed in a 34-year-old female rhesus macaque (Macaca mulatta). The tumor caused partial obstruction of the ascending colon and histologically resembled the commonly described napkin-ring tumors of the descending and sigmoid colon found in humans. Serum levels of CA 125, a high-molecular-weight glycoprotein antigen that has been reported elevated in a variety of pathological conditions of the pelvic cavity in humans, was severely elevated. Both the adenocarcinoma and the endometriosis may have contributed to this finding.

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KW - Colonic adenocarcinoma

KW - Endometriosis

KW - Rhesus macaque

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