TY - JOUR
T1 - Colonic adenocarcinoma in a rhesus macaque (Macaca mulatta)
AU - Johnson, Eugene H.
AU - Morgenstern, Susan E.
AU - Perham, Jill M.
AU - Barthold, Stephen W.
PY - 1996/12
Y1 - 1996/12
N2 - A spontaneous colonic adenocarcinoma and endometriosis was diagnosed in a 34-year-old female rhesus macaque (Macaca mulatta). The tumor caused partial obstruction of the ascending colon and histologically resembled the commonly described napkin-ring tumors of the descending and sigmoid colon found in humans. Serum levels of CA 125, a high-molecular-weight glycoprotein antigen that has been reported elevated in a variety of pathological conditions of the pelvic cavity in humans, was severely elevated. Both the adenocarcinoma and the endometriosis may have contributed to this finding.
AB - A spontaneous colonic adenocarcinoma and endometriosis was diagnosed in a 34-year-old female rhesus macaque (Macaca mulatta). The tumor caused partial obstruction of the ascending colon and histologically resembled the commonly described napkin-ring tumors of the descending and sigmoid colon found in humans. Serum levels of CA 125, a high-molecular-weight glycoprotein antigen that has been reported elevated in a variety of pathological conditions of the pelvic cavity in humans, was severely elevated. Both the adenocarcinoma and the endometriosis may have contributed to this finding.
KW - CA-125
KW - Colonic adenocarcinoma
KW - Endometriosis
KW - Rhesus macaque
UR - http://www.scopus.com/inward/record.url?scp=0030323926&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030323926&partnerID=8YFLogxK
U2 - 10.1111/j.1600-0684.1996.tb00040.x
DO - 10.1111/j.1600-0684.1996.tb00040.x
M3 - Article
C2 - 9210029
AN - SCOPUS:0030323926
SN - 0047-2565
VL - 25
SP - 435
EP - 438
JO - Journal of Medical Primatology
JF - Journal of Medical Primatology
IS - 6
ER -