Chemoenzymatic synthesis of idesolide from benzoic acid

David R. Adams; Christian Aichinger; Uwe Rinner; Tomas Hudlicky

doi:10.1055/s-0030-1259694

Chemoenzymatic synthesis of idesolide from benzoic acid

David R. Adams, Christian Aichinger, Uwe Rinner, Tomas Hudlicky^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Idesolide was synthesized in five steps from benzoic acid by base-catalyzed dimerization of hydroxy keto ester, obtained from diol, the product of the whole-cell fermentation of benzoic acid with R. eutrophus B9.

Original language	English
Article number	S00511ST
Pages (from-to)	725-729
Number of pages	5
Journal	Synlett
Issue number	5
DOIs	https://doi.org/10.1055/s-0030-1259694
Publication status	Published - 2011

Keywords

benzoic acid
diol
hydroxy keto ester
idesolide
whole-cell fermentation

ASJC Scopus subject areas

Organic Chemistry

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10.1055/s-0030-1259694

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@article{1bfb4085a106408c912323a451d68887,

title = "Chemoenzymatic synthesis of idesolide from benzoic acid",

abstract = "Idesolide was synthesized in five steps from benzoic acid by base-catalyzed dimerization of hydroxy keto ester, obtained from diol, the product of the whole-cell fermentation of benzoic acid with R. eutrophus B9.",

keywords = "benzoic acid, diol, hydroxy keto ester, idesolide, whole-cell fermentation",

author = "Adams, {David R.} and Christian Aichinger and Uwe Rinner and Tomas Hudlicky",

year = "2011",

doi = "10.1055/s-0030-1259694",

language = "English",

pages = "725--729",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "5",

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TY - JOUR

T1 - Chemoenzymatic synthesis of idesolide from benzoic acid

AU - Adams, David R.

AU - Aichinger, Christian

AU - Rinner, Uwe

AU - Hudlicky, Tomas

PY - 2011

Y1 - 2011

N2 - Idesolide was synthesized in five steps from benzoic acid by base-catalyzed dimerization of hydroxy keto ester, obtained from diol, the product of the whole-cell fermentation of benzoic acid with R. eutrophus B9.

AB - Idesolide was synthesized in five steps from benzoic acid by base-catalyzed dimerization of hydroxy keto ester, obtained from diol, the product of the whole-cell fermentation of benzoic acid with R. eutrophus B9.

KW - benzoic acid

KW - diol

KW - hydroxy keto ester

KW - idesolide

KW - whole-cell fermentation

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U2 - 10.1055/s-0030-1259694

DO - 10.1055/s-0030-1259694

M3 - Article

AN - SCOPUS:79952445984

SN - 0936-5214

SP - 725

EP - 729

JO - Synlett

JF - Synlett

IS - 5

M1 - S00511ST

ER -

Chemoenzymatic synthesis of idesolide from benzoic acid

Abstract

Keywords

ASJC Scopus subject areas

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