Chemoenzymatic synthesis of idesolide from benzoic acid

David R. Adams, Christian Aichinger, Uwe Rinner, Tomas Hudlicky*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

Idesolide was synthesized in five steps from benzoic acid by base-catalyzed dimerization of hydroxy keto ester, obtained from diol, the product of the whole-cell fermentation of benzoic acid with R. eutrophus B9.

Original languageEnglish
Article numberS00511ST
Pages (from-to)725-729
Number of pages5
JournalSynlett
Issue number5
DOIs
Publication statusPublished - 2011

Keywords

  • benzoic acid
  • diol
  • hydroxy keto ester
  • idesolide
  • whole-cell fermentation

ASJC Scopus subject areas

  • Organic Chemistry

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