Abstract
BACKGROUND: Earlier studies showed a short-term impairment of cardio-autonomic functions following coronary artery bypass grafting (CABG). There is a lack of consistency in the time of recovery from this impairment. Studies have attributed the post-CABG atrial fibrillation to preexisting obstructive sleep apnea (OSA) without an objective sleep assessment. The aim of this study was to evaluate the effect of CABG on cardio-autonomic and hemodynamic functions and on OSA indices in patients with ischemic heart disease (IHD). METHODS: Cardio-autonomic function using heart rate variability indices, hemodynamic parameters, and sleep studies were performed in 26 patients with stable IHD before, on day-6, and day-30 post-CABG surgery. RESULTS: The high-frequency powers of normalized R-R intervals significantly (P = 0.002) increased from the preoperative value of 46.09 to 66.52 on day-6 and remained unchanged on day-30 postsurgery. In contrary, the low-frequency powers of normalized R-R interval decreased from 53.91 to 33.48 during the same period (P = 0.002) and remained unchanged on day 30 postsurgery. Baroreceptor sensitivity, obstructive and central apnea indices, desaturation index, and lowest O2 saturation were not significantly different between preoperative, day-6, and day-30 postsurgery. CONCLUSION: Our study revealed that recovery of autonomic functions following CABG occurs as early as 30 days of postsurgery. CABG does not seem to have short-term effects on sleep study indices. However, long-term effects need further evaluation.
| Original language | English |
|---|---|
| Pages (from-to) | 14-21 |
| Number of pages | 8 |
| Journal | Annals of Thoracic Medicine |
| Volume | 13 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1 2018 |
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Keywords
- Apnea/hypopnea index
- heart rate variability (HRV)
- ischemic heart disease (IHD)
- sympathetic component
- vagal component
ASJC Scopus subject areas
- Surgery
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine
Cite this
Cardio-autonomic functions and sleep indices before and after coronary artery bypass surgery. / Al-Hashmi, Khamis Mohammed; Al-Abri, Mohammed; Jaju, Deepali; Mukaddirov, Mirdavron; Hossen, Abdulnasir; Hassan, Mohammed; Mesbah, Mostafa; Al-Sabti, Hilal.
In: Annals of Thoracic Medicine, Vol. 13, No. 1, 01.01.2018, p. 14-21.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cardio-autonomic functions and sleep indices before and after coronary artery bypass surgery
AU - Al-Hashmi, Khamis Mohammed
AU - Al-Abri, Mohammed
AU - Jaju, Deepali
AU - Mukaddirov, Mirdavron
AU - Hossen, Abdulnasir
AU - Hassan, Mohammed
AU - Mesbah, Mostafa
AU - Al-Sabti, Hilal
PY - 2018/1/1
Y1 - 2018/1/1
N2 - BACKGROUND: Earlier studies showed a short-term impairment of cardio-autonomic functions following coronary artery bypass grafting (CABG). There is a lack of consistency in the time of recovery from this impairment. Studies have attributed the post-CABG atrial fibrillation to preexisting obstructive sleep apnea (OSA) without an objective sleep assessment. The aim of this study was to evaluate the effect of CABG on cardio-autonomic and hemodynamic functions and on OSA indices in patients with ischemic heart disease (IHD). METHODS: Cardio-autonomic function using heart rate variability indices, hemodynamic parameters, and sleep studies were performed in 26 patients with stable IHD before, on day-6, and day-30 post-CABG surgery. RESULTS: The high-frequency powers of normalized R-R intervals significantly (P = 0.002) increased from the preoperative value of 46.09 to 66.52 on day-6 and remained unchanged on day-30 postsurgery. In contrary, the low-frequency powers of normalized R-R interval decreased from 53.91 to 33.48 during the same period (P = 0.002) and remained unchanged on day 30 postsurgery. Baroreceptor sensitivity, obstructive and central apnea indices, desaturation index, and lowest O2 saturation were not significantly different between preoperative, day-6, and day-30 postsurgery. CONCLUSION: Our study revealed that recovery of autonomic functions following CABG occurs as early as 30 days of postsurgery. CABG does not seem to have short-term effects on sleep study indices. However, long-term effects need further evaluation.
AB - BACKGROUND: Earlier studies showed a short-term impairment of cardio-autonomic functions following coronary artery bypass grafting (CABG). There is a lack of consistency in the time of recovery from this impairment. Studies have attributed the post-CABG atrial fibrillation to preexisting obstructive sleep apnea (OSA) without an objective sleep assessment. The aim of this study was to evaluate the effect of CABG on cardio-autonomic and hemodynamic functions and on OSA indices in patients with ischemic heart disease (IHD). METHODS: Cardio-autonomic function using heart rate variability indices, hemodynamic parameters, and sleep studies were performed in 26 patients with stable IHD before, on day-6, and day-30 post-CABG surgery. RESULTS: The high-frequency powers of normalized R-R intervals significantly (P = 0.002) increased from the preoperative value of 46.09 to 66.52 on day-6 and remained unchanged on day-30 postsurgery. In contrary, the low-frequency powers of normalized R-R interval decreased from 53.91 to 33.48 during the same period (P = 0.002) and remained unchanged on day 30 postsurgery. Baroreceptor sensitivity, obstructive and central apnea indices, desaturation index, and lowest O2 saturation were not significantly different between preoperative, day-6, and day-30 postsurgery. CONCLUSION: Our study revealed that recovery of autonomic functions following CABG occurs as early as 30 days of postsurgery. CABG does not seem to have short-term effects on sleep study indices. However, long-term effects need further evaluation.
KW - Apnea/hypopnea index
KW - heart rate variability (HRV)
KW - ischemic heart disease (IHD)
KW - sympathetic component
KW - vagal component
UR - http://www.scopus.com/inward/record.url?scp=85040444667&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85040444667&partnerID=8YFLogxK
U2 - 10.4103/atm.ATM_226_17
DO - 10.4103/atm.ATM_226_17
M3 - Article
VL - 13
SP - 14
EP - 21
JO - Annals of Thoracic Medicine
JF - Annals of Thoracic Medicine
SN - 1817-1737
IS - 1
ER -