Borna disease in a dog with lethal meningoencephalitis

H. Weissenbock; N. Nowotny; P. Caplazi; J. Kolodziejek; F. Ehrensperger

Borna disease in a dog with lethal meningoencephalitis

H. Weissenbock^*, N. Nowotny, P. Caplazi, J. Kolodziejek, F. Ehrensperger

^*Corresponding author for this work

Microbiology & Immunology

Research output: Contribution to journal › Article › peer-review

64 Citations (Scopus)

Abstract

A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.

Original language	English
Pages (from-to)	2127-2130
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	36
Issue number	7
Publication status	Published - 1998

ASJC Scopus subject areas

Microbiology (medical)
Microbiology

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Cite this

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title = "Borna disease in a dog with lethal meningoencephalitis",

abstract = "A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.",

author = "H. Weissenbock and N. Nowotny and P. Caplazi and J. Kolodziejek and F. Ehrensperger",

year = "1998",

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AU - Nowotny, N.

AU - Caplazi, P.

AU - Kolodziejek, J.

AU - Ehrensperger, F.

PY - 1998

Y1 - 1998

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AB - A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.

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