Abstract
A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.
| Original language | English |
|---|---|
| Pages (from-to) | 2127-2130 |
| Number of pages | 4 |
| Journal | Journal of Clinical Microbiology |
| Volume | 36 |
| Issue number | 7 |
| Publication status | Published - 1998 |
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ASJC Scopus subject areas
- Microbiology (medical)
- Microbiology
Cite this
Borna disease in a dog with lethal meningoencephalitis. / Weissenbock, H.; Nowotny, N.; Caplazi, P.; Kolodziejek, J.; Ehrensperger, F.
In: Journal of Clinical Microbiology, Vol. 36, No. 7, 1998, p. 2127-2130.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Borna disease in a dog with lethal meningoencephalitis
AU - Weissenbock, H.
AU - Nowotny, N.
AU - Caplazi, P.
AU - Kolodziejek, J.
AU - Ehrensperger, F.
PY - 1998
Y1 - 1998
N2 - A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.
AB - A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.
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UR - http://www.scopus.com/inward/citedby.url?scp=0031838460&partnerID=8YFLogxK
M3 - Article
C2 - 9650982
AN - SCOPUS:0031838460
VL - 36
SP - 2127
EP - 2130
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
SN - 0095-1137
IS - 7
ER -