Borna disease in a dog with lethal meningoencephalitis

H. Weissenbock, N. Nowotny, P. Caplazi, J. Kolodziejek, F. Ehrensperger

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.

Original languageEnglish
Pages (from-to)2127-2130
Number of pages4
JournalJournal of Clinical Microbiology
Volume36
Issue number7
Publication statusPublished - 1998

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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  • Cite this

    Weissenbock, H., Nowotny, N., Caplazi, P., Kolodziejek, J., & Ehrensperger, F. (1998). Borna disease in a dog with lethal meningoencephalitis. Journal of Clinical Microbiology, 36(7), 2127-2130.