TY - JOUR
T1 - Borna disease in a dog with lethal meningoencephalitis
AU - Weissenbock, H.
AU - Nowotny, N.
AU - Caplazi, P.
AU - Kolodziejek, J.
AU - Ehrensperger, F.
PY - 1998
Y1 - 1998
N2 - A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.
AB - A dog was euthanatized because of progressive neurological signs. Histologically, a nonsuppurative meningoencephalitis was found. By immunohistochemistry, in situ hybridization, and nested PCR procedures, Borna disease virus (BDV) antigen and BDV-specific RNA were demonstrated in brain tissues of the dog. The nucleotide sequence of the PCR product showed 94 to 98% homology to published BDV sequences. This is the first description of Borna disease in a dog.
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U2 - 10.1128/jcm.36.7.2127-2130.1998
DO - 10.1128/jcm.36.7.2127-2130.1998
M3 - Article
C2 - 9650982
AN - SCOPUS:0031838460
VL - 36
SP - 2127
EP - 2130
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
SN - 0095-1137
IS - 7
ER -