TY - JOUR
T1 - Autoimmune thyroiditis, adrenalitis and oophoritis
AU - Edmonds, Merrill
AU - Lamki, Lamk
AU - Killinger, Donald W.
AU - Volpé, Robert
N1 - Funding Information:
From the Department of Medicine, University of Toronto, and the Clinical Investigation Unit, The Wellesley Hospital, Toronto, Ontario, Canada. This investigation was supported in part by the Medical Research Council of Canada (MT 8591. Requests for reprints should be addressed to Dr. Robert Volpe, Clinical Investigation Unit, The Wellesley Hospital, Toronto, Ontario, Canada. Manuscript accepted August 16, 1972.
PY - 1973/6
Y1 - 1973/6
N2 - Described here is a young woman suffering from autoimmune thyroiditis, adrenalitis and oophoritis. This patient was carefully investigated by endocrine studies, with humoral antibodies to thyroid and adrenal, and the release of migration inhibition factor by her lymphocytes when cultured with thyroid, adrenal and ovarian antigens. Cell-mediated immunity appears to be the most important factor in the pathogenesis of these closely related disorders. A discussion of the interrelationship of these organ-specific autoimmune endocrine gland disorders is presented.
AB - Described here is a young woman suffering from autoimmune thyroiditis, adrenalitis and oophoritis. This patient was carefully investigated by endocrine studies, with humoral antibodies to thyroid and adrenal, and the release of migration inhibition factor by her lymphocytes when cultured with thyroid, adrenal and ovarian antigens. Cell-mediated immunity appears to be the most important factor in the pathogenesis of these closely related disorders. A discussion of the interrelationship of these organ-specific autoimmune endocrine gland disorders is presented.
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U2 - 10.1016/0002-9343(73)90066-1
DO - 10.1016/0002-9343(73)90066-1
M3 - Article
C2 - 4740043
AN - SCOPUS:0015633918
SN - 0002-9343
VL - 54
SP - 782
EP - 787
JO - The American Journal of Medicine
JF - The American Journal of Medicine
IS - 6
ER -