Abstract
Pulmonary hypertension is frequently associated with atrial septal defect and various connective tissue disorders. This case describes a 74-year-old woman who presented with symptoms of heart failure and concomitant involvement of salivary glands and keratoconjunctivitis. An echocardiogram demonstrated ostium secundum atrial septal defect with left to right shunt and severe pulmonary hypertension. Laboratory investigations confirmed the diagnosis of Sjögren's syndrome (SS) with positive anti-nuclear factor and centromere SS-A/Ro pattern. Anti-Ro (SS-A) was found positive. Atrial septal defect was closed through transcatheter route with significant improvement in clinical outcome. This case report suggests a possible association of atrial septal defect with primary Sjögren's syndrome in an adult patient.
| Original language | English |
|---|---|
| Pages (from-to) | 441-443 |
| Number of pages | 3 |
| Journal | Journal of the College of Physicians and Surgeons Pakistan |
| Volume | 24 |
| Issue number | 6 |
| Publication status | Published - 2014 |
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Keywords
- Ostium secundum atrial septal defect
- Pulmonary hypertension
- Sjögren's syndrome
ASJC Scopus subject areas
- Medicine(all)
Cite this
Atrial septal defect coexistent with sjögren's syndrome. / Ahmad, Farook; Sadiq, Muhammad Athar; Chee, Kok Han; Zuhdi, Ahmad Syadi Mahmood; Ahmad, Wan Azman Wan.
In: Journal of the College of Physicians and Surgeons Pakistan, Vol. 24, No. 6, 2014, p. 441-443.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Atrial septal defect coexistent with sjögren's syndrome
AU - Ahmad, Farook
AU - Sadiq, Muhammad Athar
AU - Chee, Kok Han
AU - Zuhdi, Ahmad Syadi Mahmood
AU - Ahmad, Wan Azman Wan
PY - 2014
Y1 - 2014
N2 - Pulmonary hypertension is frequently associated with atrial septal defect and various connective tissue disorders. This case describes a 74-year-old woman who presented with symptoms of heart failure and concomitant involvement of salivary glands and keratoconjunctivitis. An echocardiogram demonstrated ostium secundum atrial septal defect with left to right shunt and severe pulmonary hypertension. Laboratory investigations confirmed the diagnosis of Sjögren's syndrome (SS) with positive anti-nuclear factor and centromere SS-A/Ro pattern. Anti-Ro (SS-A) was found positive. Atrial septal defect was closed through transcatheter route with significant improvement in clinical outcome. This case report suggests a possible association of atrial septal defect with primary Sjögren's syndrome in an adult patient.
AB - Pulmonary hypertension is frequently associated with atrial septal defect and various connective tissue disorders. This case describes a 74-year-old woman who presented with symptoms of heart failure and concomitant involvement of salivary glands and keratoconjunctivitis. An echocardiogram demonstrated ostium secundum atrial septal defect with left to right shunt and severe pulmonary hypertension. Laboratory investigations confirmed the diagnosis of Sjögren's syndrome (SS) with positive anti-nuclear factor and centromere SS-A/Ro pattern. Anti-Ro (SS-A) was found positive. Atrial septal defect was closed through transcatheter route with significant improvement in clinical outcome. This case report suggests a possible association of atrial septal defect with primary Sjögren's syndrome in an adult patient.
KW - Ostium secundum atrial septal defect
KW - Pulmonary hypertension
KW - Sjögren's syndrome
UR - http://www.scopus.com/inward/record.url?scp=84902266879&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84902266879&partnerID=8YFLogxK
M3 - Article
VL - 24
SP - 441
EP - 443
JO - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
JF - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
SN - 1022-386X
IS - 6
ER -