Anxiety and depression in patients with coronary heart disease: A study in a tertiary hospital

Ho Siew Eng, Loo Chee Yean, Srijit Das, Santhna Letchmi, Khor Sin Yee, Rohayu A. Bakar, Jeliha Hung, Choy Yin Choy

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23 Citations (Scopus)


Anxiety and depression could reduce the quality of life, and exacerbate physical symptoms and even mortality amongst patients with coronary heart disease (CHD). The aim of this study was to investigate the incidence of anxiety and depression in patients with acute CHD. In a period from March to December 2008, the views of 108 CHD patients, hospitalized in a tertiary hospital, were solicited using Hospital Anxiety and Depression Scale (HADS) and sociodemographic questionnaires. Patients with CHD had a low level anxiety and depression scores. There was significant differences in the total HADS score of participants stratified for marital status (P=0.027) or co-morbidity of diseases (P=0.012). Also, there were significant differences in the scores of depression subscale stratified for marital status (P=0.021) or co-morbidity of disease (P=0.007). However, there was no significant difference between the total HADS score or depression subscale score of the participants stratified based on age, gender, race, education, or income. Moreover, unmarried CHD respondents possessed higher depression level compared to the married respondents, and CHD respondents with co-morbid diseases showed a high level of depression. The findings might be taken as evidence to suggest that CHD patients should be evaluated early for the detection of anxiety and depression for appropriate referral and support.

Original languageEnglish
Pages (from-to)201-206
Number of pages6
JournalIranian Journal of Medical Sciences
Issue number3
Publication statusPublished - Sept 2011
Externally publishedYes


  • Coronary heart disease anxiety depression quality of life

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology (miscellaneous)
  • Immunology and Microbiology (miscellaneous)
  • Clinical Psychology
  • Pharmacology, Toxicology and Pharmaceutics (miscellaneous)


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