A flavone fluorescent probe for cysteine detection

Saleh N. Al-Busafi*, Salma M. Al-Kindi, Fakhr Eldin O. Suliman, Aliya A. Al-Kalbani

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


A new blue-emitting fluorescent probe 1 based on flavone structure was prepared for the selective detection of cysteine. The probe was prepared through three synthetic steps from commercially available starting materials. Selective detection of cysteine by probe 1 in the presence of other non-thiol amino acids was established by UV-visible and fluorescent experiments. A remarkable fluorescence emission was observed at 469 nm when cysteine was mixed with probe 1. The Michael addition reaction of cysteine to probe-1 was confirmed by 1H NMR technique.

Original languageEnglish
Pages (from-to)2909-2914
Number of pages6
JournalAsian Journal of Chemistry
Issue number12
Publication statusPublished - 2019
Externally publishedYes


  • Cysteine
  • Flavone
  • Fluorescent
  • Michael addition reaction

ASJC Scopus subject areas

  • Chemistry(all)


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