An efficient regio- and stereoselective method for the synthesis of cyclic trithiocarbonates on carbohydrate skeleton is described. A freshly prepared solution of sodium trithiocarbonate reacts with cis-oriented epoxytriflate pentoses 7-11 to yield the corresponding cyclic trithiocarbonates 12-16. Structures of all new compounds are established through MS, 1H and 13C NMR techniques.
|Number of pages||3|
|Publication status||Published - Jan 6 2003|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry