Mohamed Boulassel

Dr.

Former affiliation
  • 5019 Citations
  • 29 h-Index
20012018

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Research Output

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2018

Hemoglobin F as a predictor of health-related quality of life in children with sickle cell anemia

Boulassel, M., Al-Badi, A., Elshinawy, M., Al-Hinai, J., Al Saadoon, M., Al-Qarni, Z., Khan, H., Qureshi, R. N. & Wali, Y., Jan 1 2018, (Accepted/In press) In : Quality of Life Research.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Regulatory B Cells Are Functionally Impaired in Patients Having Hemophilia A With Inhibitors

Boulassel, M. R., Al-Ghonimi, M., Al-Balushi, B., Al-Naamani, A., Al-Qarni, Z., Wali, Y., Elshinawy, M., Al-Shezawi, M., Khan, H., Nazir, H., Khater, D., Pathare, A. & Al-Kindi, S., May 1 2018, In : Clinical and Applied Thrombosis/Hemostasis. 24, 4, p. 618-624 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

Leishmania infantum and Epstein-Barr virus co-infection in a patient with hemophagocytosis

Gaifer, Z. & Boulassel, M. R., 2016, In : Infectious Disease Reports. 8, 4, p. 78-79 2 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2015

Accuracy of platelet counting by optical and impedance methods in patients with thrombocytopaenia and microcytosis

Boulassel, M. R., Al-Farsi, R., Al-Hashmi, S., Al-Riyami, H., Khan, H. & Al-Kindi, S., Nov 1 2015, In : Sultan Qaboos University Medical Journal. 15, 4, p. e463-e468

Research output: Contribution to journalArticle

4 Citations (Scopus)
2014

Decreases in Colonic and Systemic Inflammation in Chronic HIV Infection after IL-7 Administration

Sereti, I., Estes, J. D., Thompson, W. L., Morcock, D. R., Fischl, M. A., Croughs, T., Beq, S., Lafaye de Micheaux, S., Yao, M. D., Ober, A., Wilson, E. M. P., Natarajan, V., Imamichi, H., Boulassel, M. R., Lederman, M. M. & Routy, J. P., Jan 2014, In : PLoS Pathogens. 10, 1, e1003890.

Research output: Contribution to journalArticle

57 Citations (Scopus)
2013

HLA-DO increases bacterial superantigen binding to human MHC molecules by inhibiting dissociation of class II-associated invariant chain peptides

Pezeshki, A. M., Azar, G. A., Mourad, W., Routy, J. P., Boulassel, M. R., Denzin, L. K. & Thibodeau, J., Oct 2013, In : Human Immunology. 74, 10, p. 1280-1287 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Multiple cycles of rituximab therapy in chronic refractory immune thrombocytopenia: A case report with a 10-year follow-up

Routy, B., Boulassel, M. R., Spurll, G. M., Warner, M. N. & Routy, J. P., Mar 2013, In : American Journal of Therapeutics. 20, 2, p. 219-222 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Programmed death-1 is a marker for abnormal distribution of naive/memory T cell subsets in HIV-1 infection

Breton, G., Chomont, N., Takata, H., Fromentin, R., Ahlers, J., Filali-Mouhim, A., Riou, C., Boulassel, M. R., Routy, J. P., Yassine-Diab, B. & Sékaly, R. P., Sep 1 2013, In : Journal of Immunology. 191, 5, p. 2194-2204 11 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
2012

Assessing risk of a short-term antiretroviral therapy discontinuation as a read-out of viral control in immune-based therapy

Routy, J. P., Boulassel, M. R., Nicolette, C. A. & Jacobson, J. M., Jun 2012, In : Journal of Medical Virology. 84, 6, p. 885-889 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Autologous HIV-1 Clade-B Nef Peptides Elicit Increased Frequency, Breadth and Function of CD8+ T-Cells Compared to Consensus Peptides

Doroudchi, M., Yegorov, O., Baumgartner, T., Kernaleguen, A. E., Breton, G., Ndongala, M. L., Boulassel, M. R., Routy, J. P., Bernard, N. F., Sékaly, R. P. & Yassine-Diab, B., Nov 19 2012, In : PLoS One. 7, 11, e49562.

Research output: Contribution to journalArticle

5 Citations (Scopus)

CD160 and PD-1 Co-Expression on HIV-Specific CD8 T Cells Defines a Subset with Advanced Dysfunction

Peretz, Y., He, Z., Shi, Y., Yassine-Diab, B., Goulet, J. P., Bordi, R., Filali-Mouhim, A., Loubert, J. B., El-Far, M., Dupuy, F. P., Boulassel, M. R., Tremblay, C., Routy, J. P., Bernard, N., Balderas, R., Haddad, E. K. & Sékaly, R. P., Aug 2012, In : PLoS Pathogens. 8, 8, e1002840.

Research output: Contribution to journalArticle

91 Citations (Scopus)

CD4 T cell nadir independently predicts the magnitude of the HIV reservoir after prolonged suppressive antiretroviral therapy

Boulassel, M. R., Chomont, N., Pai, N. P., Gilmore, N., Sékaly, R. P. & Routy, J. P., Jan 2012, In : Journal of Clinical Virology. 53, 1, p. 29-32 4 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation

Janbazian, L., Price, D. A., Canderan, G., Filali-Mouhim, A., Asher, T. E., Ambrozak, D. R., Scheinberg, P., Boulassel, M. R., Routy, J. P., Koup, R. A., Douek, D. C., Sekaly, R. P. & Trautmann, L., Feb 1 2012, In : Journal of Immunology. 188, 3, p. 1156-1167 12 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis (Journal of Clinical Investigation (2011) 121, 10 (3877-3888) DOI: 10.1172/JCI59211)

Van Grevenynghe, J., Cubas, R. A., Noto, A., DaFonseca, S., He, Z., Peretz, Y., Filali-Mouhim, A., Dupuy, F. P., Procopio, F. A., Chomont, N., Balderas, R. S., Said, E. A., Boulassel, M. R., Tremblay, C. L., Routy, J. P., Sékaly, R. P. & Haddad, E. K., Jul 2 2012, In : Journal of Clinical Investigation. 122, 7, p. 2704 1 p.

Research output: Contribution to journalArticle

New cellular weapon to kill leukaemic B-cells

Boulassel, M. R., May 2012, In : Sultan Qaboos University Medical Journal. 12, 2, p. 137-152 16 p.

Research output: Contribution to journalArticle

Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection

Trautmann, L., Mbitikon-Kobo, F. M., Goulet, J. P., Peretz, Y., Shi, Y., Van Grevenynghe, J., Procopio, F. A., Boulassel, M. R., Routy, J. P., Chomont, N., Haddad, E. K. & Sekaly, R. P., Oct 25 2012, In : Blood. 120, 17, p. 3466-3477 12 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

The colocalization potential of HIV-specific CD8 + and CD4 + T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid

Wacleche, V. S., Chomont, N., Gosselin, A., Monteiro, P., Goupil, M., Kared, H., Tremblay, C., Bernard, N., Boulassel, M. R., Routy, J. P. & Ancuta, P., Mar 28 2012, In : PLoS One. 7, 3, e32964.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The effect of β-carotene supplementation on the pharmacokinetics of nelfinavir and its active metabolite M8 in HIV-1-infected patients

Sheehan, N. L., Van Heeswijk, R. P. G., Foster, B. C., Akhtar, H., Singhal, N., Seguin, I., DelBalso, L., Bourbeau, M., Chauhan, B. M., Boulassel, M. R., Burger, D. M., Lalonde, R. G. & Cameron, D. W., Jan 2012, In : Molecules. 17, 1, p. 688-702 15 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: Results from a multicentre randomized clinical study

Routy, J. P., Tremblay, C. L., Angel, J. B., Trottier, B., Rouleau, D., Baril, J. G., Harris, M., Trottier, S., Singer, J., Chomont, N., Sékaly, R. P. & Boulassel, M. R., May 2012, In : HIV Medicine. 13, 5, p. 291-296 6 p.

Research output: Contribution to journalArticle

79 Citations (Scopus)
2011

A novel and simplified method of culture of human blood-derived early endothelial progenitor cells for the treatment of ischemic vascular disease

Bouchentouf, M., Forner, K., Cuerquis, J., Boulassel, M. R., Routy, J. P., Waller, E. K., Quyyumi, A. A., Paradis, P., Schiffrin, E. L. & Galipeau, J., 2011, In : Cell Transplantation. 20, 9, p. 1431-1443 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Effect of antiretroviral therapy on HIV-1 genetic evolution during acute infection

Chamberland, A., Sylla, M., Boulassel, M. R., Baril, J. G., Côté, P., Thomas, R., Trottier, B., Rouleau, D., Routy, J. P. & Tremblay, C., Mar 2011, In : International Journal of STD and AIDS. 22, 3, p. 146-150 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Forced expression of HLA-DM at the surface of dendritic cells increases loading of synthetic peptides on MHC class II molecules and modulates T cell responses

Pezeshki, A. M., Côté, M. H., Azar, G. A., Routy, J. P., Boulassel, M. R. & Thibodeau, J., Jul 1 2011, In : Journal of Immunology. 187, 1, p. 74-81 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis

Van Grevenynghe, J., Cubas, R. A., Noto, A., DaFonseca, S., He, Z., Peretz, Y., Filali-Mouhim, A., Dupuy, F. P., Procopio, F. A., Chomont, N., Balderas, R. S., Said, E. A., Boulassel, M. R., Tremblay, C. L., Routy, J. P., Sékaly, R. P. & Haddad, E. K., Oct 3 2011, In : Journal of Clinical Investigation. 121, 10, p. 3877-3888 12 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7

Monteiro, P., Gosselin, A., Wacleche, V. S., El-Far, M., Said, E. A., Kared, H., Grandvaux, N., Boulassel, M. R., Routy, J. P. & Ancuta, P., Apr 15 2011, In : Journal of Immunology. 186, 8, p. 4618-4630 13 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Receptor-ligand requirements for increased NK cell polyfunctional potential in slow progressors infected with HIV-1 coexpressing KIR3DL1*h/*y and HLA-B*57

Kamya, P., Boulet, S., Tsoukas, C. M., Routy, J. P., Thomas, R., Côté, P., Boulassel, M. R., Baril, J. G., Kovacs, C., Migueles, S. A., Connors, M., Suscovich, T. J., Brander, C., Tremblay, C. L. & Bernard, N., Jun 2011, In : Journal of Virology. 85, 12, p. 5949-5960 12 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Relative contribution of HIV-specific functional lymphocyte subsets restricted by protective and non-protective HLA alleles

Peretz, Y., Marra, O., Thomas, R., Legault, D., Côté, P., Boulassel, M. R., Rouleau, D., Routy, J. P., Sékaly, R. P., Tsoukas, C. M., Tremblay, C. & Bernard, N. F., Jun 1 2011, In : Viral Immunology. 24, 3, p. 189-198 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2010

Changes in function of HIV-specific T-cell responses with increasing time from infection

Ndongala, M. L., Kamya, P., Boulet, S., Peretz, Y., Rouleau, D., Tremblay, C., Leblanc, R., Côté, P., Baril, J. G., Thomas, R., Vézina, S., Boulassel, M. R., Routy, J. P., Sékaly, R. P. & Bernard, N. F., Apr 1 2010, In : Viral Immunology. 23, 2, p. 159-168 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Dynamics and consequences of IL-21 production in HIV-infected individuals: A longitudinal and cross-sectional study

Iannello, A., Boulassel, M. R., Samarani, S., Debbeche, O., Tremblay, C., Toma, E., Routy, J. P. & Ahmad, A., Jan 1 2010, In : Journal of Immunology. 184, 1, p. 114-126 13 p.

Research output: Contribution to journalArticle

114 Citations (Scopus)

HIV-1 causes an imbalance in the production of interleukin-18 and Its natural antagonist in HIV-infected individuals: Implications for enhanced viral replication

Iannello, A., Boulassel, M. R., Samarani, S., Tremblay, C., Toma, E., Routy, J. P. & Ahmad, A., Feb 15 2010, In : Journal of Infectious Diseases. 201, 4, p. 608-617 10 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

IL-21 enhances NK cell functions and survival in healthy and HIV-infected patients with minimal stimulation of viral replication

Iannello, A., Boulassel, M. R., Samarani, S., Tremblay, C., Toma, E., Routy, J. P. & Ahmad, A., May 2010, In : Journal of Leukocyte Biology. 87, 5, p. 857-867 11 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy

Routy, J. P., Boulassel, M. R., Yassine-Diab, B., Nicolette, C., Healey, D., Jain, R., Landry, C., Yegorov, O., Tcherepanova, I., Monesmith, T., Finke, L. & Sékaly, R. P., Feb 2010, In : Clinical Immunology. 134, 2, p. 140-147 8 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

Monocyte derivatives promote angiogenesis and myocyte survival in a model of myocardial infarction

Bouchentouf, M., Paradis, P., Forner, K. A., Cuerquis, J., Boivin, M. N., Zheng, J., Boulassel, M. R., Routy, J. P., Schiffrin, E. L. & Galipeau, J., 2010, In : Cell Transplantation. 19, 4, p. 369-386 18 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Peripheral blood CCR4+CCR6+ and CXCR3 +CCR6+ CD4+ T cells are highly permissive to HIV-1 infection

Gosselin, A., Monteiro, P., Chomont, N., Diaz-Griffero, F., Said, E. A., Fonseca, S., Wacleche, V., El-Far, M., Boulassel, M. R., Routy, J. P., Sekaly, R. P. & Ancuta, P., Feb 1 2010, In : Journal of Immunology. 184, 3, p. 1604-1616 13 p.

Research output: Contribution to journalArticle

178 Citations (Scopus)

Programmed death-1-induced interleukin-10 production by monocytes impairs CD4 + T cell activation during HIV infection

Said, E. A., Dupuy, F. P., Trautmann, L., Zhang, Y., Shi, Y., El-Far, M., Hill, B. J., Noto, A., Ancuta, P., Peretz, Y., Fonseca, S. G., Van Grevenynghe, J., Boulassel, M. R., Bruneau, J., Shoukry, N. H., Routy, J. P., Douek, D. C., Haddad, E. K. & Sekaly, R. P., Apr 2010, In : Nature Medicine. 16, 4, p. 452-459 8 p.

Research output: Contribution to journalArticle

270 Citations (Scopus)

Two distinct chimeric potexviruses share antigenic cross-presentation properties of MHC class I epitopes

Hanafi, L. A., Bolduc, M., Gagné, M. È. L., Dufour, F., Langelier, Y., Boulassel, M. R., Routy, J. P., Leclerc, D. & Lapointe, R., Aug 2010, In : Vaccine. 28, 34, p. 5617-5626 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2009

HIV Gag p24 specific responses secreting IFN-γ and/or IL-2 in treatment-naïve individuals in acute infection early disease (AIED) are associated with low viral load

Ndongala, M. L., Peretz, Y., Boulet, S., Doroudchi, M., Yassine-Diab, B., Boulassel, M. R., Rouleau, D., Tremblay, C., LeBlanc, R., Routy, J. P., Sékaly, R. P. & Bernard, N. F., May 2009, In : Clinical Immunology. 131, 2, p. 277-287 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

Chomont, N., El-Far, M., Ancuta, P., Trautmann, L., Procopio, F. A., Yassine-Diab, B., Boucher, G., Boulassel, M. R., Ghattas, G., Brenchley, J. M., Schacker, T. W., Hill, B. J., Douek, D. C., Routy, J. P., Haddad, E. K. & Sékaly, R. P., Aug 2009, In : Nature Medicine. 15, 8, p. 893-900 8 p.

Research output: Contribution to journalArticle

956 Citations (Scopus)

Human activated T lymphocytes modulate IDO expression in tumors through Th1/Th2 balance

Godin-Ethier, J., Pelletier, S., Hanafi, L. A., Gannon, P. O., Forget, M. A., Routy, J. P., Boulassel, M. R., Krzemien, U., Tanguay, S., Lattouf, J. B., Arbour, N. & Lapointe, R., Dec 15 2009, In : Journal of Immunology. 183, 12, p. 7752-7760 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

P16-54 LB. Blood CCR6+ Th17 and Th1Th17 but not CCR6neg Th1 cells are targets for HIV replication and their frequency is diminished in HIV-infected subjects

Gosselin, A., Monteiro, P., Chomont, N., Diaz-Griffero, F., Wacleche, V. S., Said, E. A., Fonseca, S., El-Far, M., Boulassel, M., Routy, J., Sekaly, R. & Ancuta, P., Oct 22 2009, In : Retrovirology. 6, SUPPL. 3, 1742.

Research output: Contribution to journalArticle

P18-13 LB. Immunogenicity of an autologous dendritic cell anti-HIV therapy in HIV-1 infected individuals

Yassine Diab, B., Coutsinos, Z., Landry, C., Gagnon, D., Sauvé, D., Hébert-Benoît, C., Hébert, V., Boulassel, M., Routy, J., Jain, R., Tcherepanova, I., Healey, D., Nicolette, C. & Sekaly, R., Oct 22 2009, In : Retrovirology. 6, SUPPL. 3, 1742.

Research output: Contribution to journalArticle

Potential role of interleukin-18 in the immunopathogenesis of AIDS: Involvement in fratricidal killing of NK cells

Iannello, A., Samarani, S., Debbeche, O., Ahmad, R., Boulassel, M. R., Tremblay, C., Toma, E., Routy, J. P. & Ahmad, A., Jun 2009, In : Journal of Virology. 83, 12, p. 5999-6010 12 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

SiRNA knockdown of PD-L1 and PD-L2 in monocyte-derived dendritic cells only modestly improves proliferative responses to gag by CD8+ T cells from HIV-1-infected individuals

Breton, G., Yassine-Diab, B., Cohn, L., Boulassel, M. R., Routy, J. P., Sékaly, R. P. & Steinman, R. M., Sep 2009, In : Journal of Clinical Immunology. 29, 5, p. 637-645 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

The immunosuppressive properties of the HIV Vpr protein are linked to a single highly conserved residue, R90

Tcherepanova, I., Starr, A., Lackford, B., Adams, M. D., Routy, J. P., Boulassel, M. R., Calderhead, D., Healey, D. & Nicolette, C., Jun 10 2009, In : PLoS One. 4, 6, e5853.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2008
1 Citation (Scopus)

Decreased levels of circulating IL-21 in HIV-infected AIDS patients: Correlation with CD4+ T-cell counts

Iannello, A., Tremblay, C., Routy, J. P., Boulassel, M. R., Toma, E. & Ahmad, A., Sep 1 2008, In : Viral Immunology. 21, 3, p. 385-388 4 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

HHV-8 linked to Kaposi's sarcoma, Castleman's disease and primary effusion lymphoma in a HIV-1-infected man

Bestawros, A., Boulassel, M. R., Michel, R. P. & Routy, J. P., Jun 2008, In : Journal of Clinical Virology. 42, 2, p. 179-181 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Persistent human immunodeficiency virus-1 antigenaemia affects the expression of interleukin-7Rα on central and effector memory CD4 + and CD8+ T cell subsets

Mercier, F., Boulassel, M. R., Yassine-Diab, B., Tremblay, C., Bernard, N. F., Sekaly, R. P. & Routy, J. P., Apr 2008, In : Clinical and Experimental Immunology. 152, 1, p. 72-80 9 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Transcription factor FOXO3a controls the persistence of memory CD4 + T cells during HIV infection

Van Grevenynghe, J., Procopio, F. A., He, Z., Chomont, N., Riou, C., Zhang, Y., Gimmig, S., Boucher, G., Wilkinson, P., Shi, Y., Yassine-Diab, B., Said, E. A., Trautmann, L., Far, M. E., Balderas, R. S., Boulassel, M. R., Routy, J. P., Haddad, E. K. & Sekaly, R. P., Mar 2008, In : Nature Medicine. 14, 3, p. 266-274 9 p.

Research output: Contribution to journalArticle

121 Citations (Scopus)
2007

A dual color ELISPOT method for the simultaneous detection of IL-2 and IFN-γ HIV-specific immune responses

Boulet, S., Ndongala, M. L., Peretz, Y., Boisvert, M. P., Boulassel, M. R., Tremblay, C., Routy, J. P., Sekaly, R. P. & Bernard, N. F., Mar 30 2007, In : Journal of Immunological Methods. 320, 1-2, p. 18-29 12 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Functional T cell subsets contribute differentially to HIV peptide-specific responses within infected individuals: Correlation of these functional T cell subsets with markers of disease progression

Peretz, Y., Ndongala, M. L., Boulet, S., Boulassel, M. R., Rouleau, D., Côté, P., Longpré, D., Routy, J. P., Falutz, J., Tremblay, C., Tsoukas, C. M., Sékaly, R. P. & Bernard, N. F., Jul 2007, In : Clinical Immunology. 124, 1, p. 57-68 12 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)