TY - JOUR
T1 - Presentation of epilepsy in a patient with Wilson's disease and developmental venous anomaly (venous angioma) in the Brain
AU - Alobaidy, Ammar
AU - Alazri, Faisal
AU - Jacob, P. C.
AU - Al-Kalbani, Jamila H.
PY - 2012/11
Y1 - 2012/11
N2 - Intracranial developmental venous anomalies (DVAs), also called venous angiomas, and Wilson's disease are both considered rare disorders with varying degrees of neurologic and systemic manifestations; yet the coexistence of the two disorders is considered extremely rare, bearing in mind the low prevalence of each disorder. Epilepsy is a recognised presentation in these disorders and will be the focus of discussion in our report of a 21-year-old male patient who, based on a clinical examination and laboratory and neuroimaging results, was diagnosed with both Wilson's disease and DVA. He presented initially at Sultan Qaboos University Hospital, Oman with tremors and writing difficulties in the right hand followed by the development of epilepsy, and was treated medically by de-coppering and antiepileptic medications. We also present a brief literature review of both disorders, their association with epilepsy, and treatment options. Family screening for patients with Wilson's disease is pivotal in preventing unfavourable outcomes.
AB - Intracranial developmental venous anomalies (DVAs), also called venous angiomas, and Wilson's disease are both considered rare disorders with varying degrees of neurologic and systemic manifestations; yet the coexistence of the two disorders is considered extremely rare, bearing in mind the low prevalence of each disorder. Epilepsy is a recognised presentation in these disorders and will be the focus of discussion in our report of a 21-year-old male patient who, based on a clinical examination and laboratory and neuroimaging results, was diagnosed with both Wilson's disease and DVA. He presented initially at Sultan Qaboos University Hospital, Oman with tremors and writing difficulties in the right hand followed by the development of epilepsy, and was treated medically by de-coppering and antiepileptic medications. We also present a brief literature review of both disorders, their association with epilepsy, and treatment options. Family screening for patients with Wilson's disease is pivotal in preventing unfavourable outcomes.
KW - Case report
KW - Epilepsy
KW - Intracranial venous angioma
KW - Oman
KW - Wilson's disease
UR - http://www.scopus.com/inward/record.url?scp=84870704347&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84870704347&partnerID=8YFLogxK
U2 - 10.12816/0003178
DO - 10.12816/0003178
M3 - Review article
AN - SCOPUS:84870704347
SN - 2075-051X
VL - 12
SP - 503
EP - 507
JO - Sultan Qaboos University Medical Journal
JF - Sultan Qaboos University Medical Journal
IS - 4
ER -