TY - JOUR
T1 - Laboratory confirmed health care-associated bloodstream infections
T2 - A Jordanian study
AU - Al-Rawajfah, Omar M.
AU - Cheema, Jehanzeb
AU - Hweidi, Issa M.
AU - Hewitt, Jeanne Beauchamp
AU - Musallam, Eyad
PY - 2012/12
Y1 - 2012/12
N2 - Background: Few studies have been conducted in Jordan related to health care associated bloodstream infections (HCABSIs). This study aims to examine epidemiology of HCABSIs among hospitalized adult patients in Jordan. Methods: A cohort study (N=570; 445 confirmed HCABSIs, 125 uninfected patients) with a nested 1:1 matched case-control design (n=125 in each group) was used based on data from one large referral hospital in Jordan over a period of 5 years. HCABSI cases were determined based on confirmed positive blood culture after 48. h of admission. The case-control analyses (n=250 per group) matched on gender, age, same admission month and unit. Results: The overall incidence and mortality rates were 8.1 and 5.8 per 1000 admissions, respectively. Four-variable and three-variable multivariate models were proposed to explain the risk of HCABSIs in the matched analyses .The four-variable model consists of blood product (OR=24.5), invasive procedures (OR=4.3), renal failure (OR=9.2), and presence of other infections (OR=21.6). The three-variable model consists of recipient of blood product (OR=19.7), invasive procedures (OR=4.5), and renal failure (OR=9.4). Conclusions: This study is a pioneer study that examined risk factors, the associated HCABSIs in Jordan. Results from this study can be used to influence infection control plans in Jordan.
AB - Background: Few studies have been conducted in Jordan related to health care associated bloodstream infections (HCABSIs). This study aims to examine epidemiology of HCABSIs among hospitalized adult patients in Jordan. Methods: A cohort study (N=570; 445 confirmed HCABSIs, 125 uninfected patients) with a nested 1:1 matched case-control design (n=125 in each group) was used based on data from one large referral hospital in Jordan over a period of 5 years. HCABSI cases were determined based on confirmed positive blood culture after 48. h of admission. The case-control analyses (n=250 per group) matched on gender, age, same admission month and unit. Results: The overall incidence and mortality rates were 8.1 and 5.8 per 1000 admissions, respectively. Four-variable and three-variable multivariate models were proposed to explain the risk of HCABSIs in the matched analyses .The four-variable model consists of blood product (OR=24.5), invasive procedures (OR=4.3), renal failure (OR=9.2), and presence of other infections (OR=21.6). The three-variable model consists of recipient of blood product (OR=19.7), invasive procedures (OR=4.5), and renal failure (OR=9.4). Conclusions: This study is a pioneer study that examined risk factors, the associated HCABSIs in Jordan. Results from this study can be used to influence infection control plans in Jordan.
KW - Bloodstream infections
KW - Charges
KW - Healthcare acquired
KW - Healthcare costs
KW - Length of stay
KW - Risk factors
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U2 - 10.1016/j.jiph.2012.08.003
DO - 10.1016/j.jiph.2012.08.003
M3 - Article
C2 - 23287611
AN - SCOPUS:84871715669
SN - 1876-0341
VL - 5
SP - 403
EP - 411
JO - Journal of Infection and Public Health
JF - Journal of Infection and Public Health
IS - 6
ER -