Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y₁₂ receptor

Pharmacology, Toxicology and Pharmaceutical Science

• Adenosine Diphosphate 100%
• Luciferase 66%
• Forskolin 33%
• Chinese Hamster 33%

Biochemistry, Genetics and Molecular Biology

• P2Y12 74%
• Response Element 37%
• Luciferase 37%
• Thrombocyte Aggregation 18%
• Concentration Response 18%

Agricultural and Biological Sciences

• P2Y12 74%
• Luciferase 37%
• Chinese Hamster Ovary Cell 18%