How do multi-modality strategies affect outcomes in T2D using a randomized control trial?

Objective: A randomized clinical trial to examine the levels of body mass index, fasting blood glucose, blood pressure and glycemic control using multi-modality strategies among adults with type 2 diabetes. Methods: A randomized control trial (RCT), two-arm, prospective, and an interventional was designed with an intervention group (IG) and a control group (CG) using stratified block randomization and triple-blinding. Adults with T2D (N = 200) were randomly assigned to an intervention group (IG, n = 100) and a control group (CG, n = 100) in a single site trial. The adults with T2D in the IG were exposed to multi-modality strategies using an animated digital video, motivational interviewing, telephone counseling and the structured diabetes education by the diabetes nurse educator. Adults in the CG were only exposed to the structured diabetes education. Body mass index (BMI), fasting blood glucose (FBG), blood pressure (BP), and glycosylated hemoglobin (HbA1c) were measured as primary outcomes. Results: The adults with T2D in the IG had significant improvements in the HbA1c (2.4%), BMI (2.8 kg/m²), and a FBG (1.8 mmol/L); and they achieved lower HbA1c levels compared to the CG. Conclusion: Multi-modality strategies were effective for lowering HbA1c and reducing BMI among adults with T2D. Implications. Integration of cognitive behavioural educational using multi-modality strategies promoted better primary outcomes among adults with T2D.