ملخص
We report an unusual case of a 40-year-old female patient with a severe case of direct Coombs positive haemolytic anaemia, moderate hepatomegaly and marked splenomegaly. Her initial response to steroids was transient and was rapidly followed by a relapse. Therefore, she underwent splenectomy both as a therapeutic measure and to rule out an underlying lymphoproliferative disorder. Histopathological examination of the excised spleen, as well a liver biopsy, revealed extensive extramedullary haematopoiesis, while significant marrow fibrosis was noted in a trephine biopsy sample. These findings confirmed the concomitant diagnosis of agnogenic myeloid metaplasia with myelofibrosis.
اللغة الأصلية | English |
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الصفحات (من إلى) | 495-499 |
عدد الصفحات | 5 |
دورية | Haematologia |
مستوى الصوت | 32 |
رقم الإصدار | 4 |
حالة النشر | Published - 2002 |
ASJC Scopus subject areas
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